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MNX1 gene

Known as: MNX1, HOMEOBOX GENE HB9, Motor Neuron and Pancreas Homeobox 1 Gene 
This gene plays a role in both the regulation of transcription and DNA binding.
National Institutes of Health

Related topics

Related topics

9 relations
Cell Differentiation processCurrarino triadHomo sapiensHumoral Immunity
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MNX1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer.
Incidence and mortality rates for prostate cancer are higher in African-American (AA) men than in European-American (EA) men, but… Expand
Highly Cited
2014
Highly Cited
2014
Analysis of Transcription Factors Key for Mouse Pancreatic Development Establishes NKX2-2 and MNX1 Mutations as Causes of Neonatal Diabetes in Man
Summary Understanding transcriptional regulation of pancreatic development is required to advance current efforts in developing… Expand
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2009
2009
MNX1 (HLXB9) mutations in Currarino patients.
PURPOSE The combination of partial absence of the sacrum, anorectal anomalies, and presacral mass constitutes Currarino syndrome… Expand
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2005
2005
HLXB9 activates IL6 in Hodgkin lymphoma cell lines and is regulated by PI3K signalling involving E2F3
Multiple cytokines are secreted by Hodgkin lymphoma (HL) cells, notably interleukin-6 (IL6), which is believed to play a… Expand
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Highly Cited
2004
Highly Cited
2004
Analysis of embryonic motoneuron gene regulation: derepression of general activators function in concert with enhancer factors
The underlying transcriptional mechanisms that establish the proper spatial and temporal pattern of gene expression required for… Expand
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Highly Cited
2004
Highly Cited
2004
Zebrafish mnx genes in endocrine and exocrine pancreas formation.
The pancreas consists of two components, which exert distinct homeostatic function, an endocrine part that secretes hormones… Expand
Highly Cited
2001
Highly Cited
2001
Spectrum of mutations and genotype–phenotype analysis in Currarino syndrome
The triad of a presacral tumour, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by… Expand
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Highly Cited
1999
Highly Cited
1999
A physical and transcriptional map of the preaxial polydactyly locus on chromosome 7q36.
Preaxial polydactyly is a congenital hand malformation that includes duplicated thumbs, various forms of triphalangeal thumbs… Expand
1999
1999
The homeodomain transcription factors Islet 1 and HB9 are expressed in adult alpha and gamma motoneurons identified by selective retrograde tracing
To study gene expression in differentiated adult motoneuron subtypes, we used fluorescent dextrans for both anterograde and… Expand
Highly Cited
1994
Highly Cited
1994
A novel human homeobox gene distantly related to proboscipedia is expressed in lymphoid and pancreatic tissues.
A novel human homeobox gene, HB9, was isolated from a cDNA library prepared from in vitro stimulated human tonsil B lymphocytes… Expand
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