FAQ

MNX1 gene

Known as: MNX1, HOMEOBOX GENE HB9, Motor Neuron and Pancreas Homeobox 1 Gene 
This gene plays a role in both the regulation of transcription and DNA binding.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2018
02419912018

Related topics

Related topics

9 relations
Cell Differentiation processCurrarino triadHomo sapiensHumoral Immunity
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MNX1 wt Allele

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
MNX1 gene
Cell Differentiation process
dna binding
Homo sapiens
Humoral Immunity
Transcriptional Regulation

Papers overview

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2013
2013
Transcription factor gene MNX1 is a novel cause of permanent neonatal diabetes in a consanguineous family.
AIM Permanent neonatal diabetes mellitus (PNDM) is a rare monogenic form of non-autoimmune diabetes. Genetic defects have been… (More)
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2011
2011
Presacral teratoma in a Curarrino syndrome woman with an unreported insertion in MNX1 gene.
OBJECTIVE Currarino syndrome (CS) comprises a presacral mass, anorectal malformation, and a sacral bony defect. It is rarely… (More)
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2009
2009
Highly Efficient Differentiation and Enrichment of Spinal Motor Neurons Derived from Human and Monkey Embryonic Stem Cells
BACKGROUND There are no cures or efficacious treatments for severe motor neuron diseases. It is extremely difficult to obtain na… (More)
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2009
2009
MNX1 (HLXB9) mutations in Currarino patients.
PURPOSE The combination of partial absence of the sacrum, anorectal anomalies, and presacral mass constitutes Currarino syndrome… (More)
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2007
2007
UNC-4 represses CEH-12/HB9 to specify synaptic inputs to VA motor neurons in C. elegans.
In Caenorhabditis elegans, VA and VB motor neurons arise as lineal sisters but synapse with different interneurons to regulate… (More)
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2006
2006
Introduction of the MASH1 gene into mouse embryonic stem cells leads to differentiation of motoneuron precursors lacking Nogo receptor expression that can be applicable for transplantation to spinal…
ES cells transfected with the MASH1 gene yielded purified spinal motoneuron precursors expressing HB9 and Islet1. The cells… (More)
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2002
2002
Drosophila HB9 is expressed in a subset of motoneurons and interneurons, where it regulates gene expression and axon pathfinding.
Motoneurons are an essential component of all metazoan nervous systems, but it is unknown whether there is an evolutionarily… (More)
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2001
2001
Spectrum of mutations and genotype–phenotype analysis in Currarino syndrome
The triad of a presacral tumour, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by… (More)
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Highly Cited
1999
Highly Cited
1999
Active Suppression of Interneuron Programs within Developing Motor Neurons Revealed by Analysis of Homeodomain Factor HB9
Sonic hedgehog (Shh) specifies the identity of both motor neurons (MNs) and interneurons with morphogen-like activity. Here, we… (More)
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1994
1994
A novel human homeobox gene distantly related to proboscipedia is expressed in lymphoid and pancreatic tissues.
A novel human homeobox gene, HB9, was isolated from a cDNA library prepared from in vitro stimulated human tonsil B lymphocytes… (More)
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