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MLL/MLLT3 Fusion Gene

Known as: MLL-AF9 Fusion Gene, MLL-MLLT3 Fusion Gene, MLL/AF9 FUSION GENE 
A fusion gene that results from a chromosomal translocation t(9;11)(p22;q23) which fuses the 5' half of the MLL gene to the 3' end of the MLLT3 gene… 
National Institutes of Health

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Related topics

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KMT2A geneMLL/MLLT3 Fusion Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The incidence and distribution characteristics of MLL rearrangements in Chinese acute myeloid leukemia patients by multiplex nested RT-PCR.
Occurrence of MLL (Mixed Lineage Leukemia) gene rearrangements indicates poor prognosis in acute myeloid leukemia (AML) patients… 
2016
2016
Abstract IA23: Leukemia development and the microenvironment
Myeloproliferative neoplasms (MPNs) are hematological malignancies originated by hematopoietic stem cells (HSCs) carrying… 
Review
2015
Review
2015
Regulation of αENaC transcription.
2013
2013
Trithorax and polycomb cooperation in MLL fusion acute leukemia
Genetic alterations of the mixed lineage leukemia 1 gene ( MLL1 , here referred to as MLL ) located on the long arm of chromosome… 
2011
2011
Acute Myeloblastic Leukaemia with Alternations of MLL Proto-Oncogene Protein (11q23/ MLL+ AML)
Súhrn U akútnej myeloblastovej leukémie je chromozómový prúžok 11q23 jedným z najčastejších zlomových regiónov. Analýza tejto… 
Review
2010
Review
2010
[Acute myeloblastic leukaemia with alternations of MLL proto-oncogene protein (11q23/MLL+ AML)].
One of the most common chromosomal breakpoint regions in acute myeloid leukaemia is the chromosome band 11q23. The analysis of… 
2006
2006
Imatinib mesylate does not impair the immunogenicity of human myeloid blood dendritic cells
Imatinib mesylate does not impair the immunogenicity of human myeloid blood dendritic cells 
2006
2006
The Mll-AF9 Knock-In Fusion Gene Results in Reprogramming and Enhanced Self-Renewal of Hematopoietic Progenitors, Especially in the HSC and CLP Populations.
The relative importance of the major hematopoietic progenitor/stem cell populations in MLL fusion gene leukemias remains largely… 
2004
2004
Emergence of translocation t(9;11)‐positive leukemia during treatment of childhood acute lymphoblastic leukemia
Therapy‐related acute myeloid leukemia (t‐AML) characterized by the t(9;11)(p22;q23) translocation is one of the most frequent… 
2004
2004
MLL-AF9 and MLL-ENL Induce Deregulation of Similar Downstream Candidate Genes: An Analysis across Experimental Protocols and Laboratories.
Expression profiling has become an important tool for understanding gene deregulation in MLL-fusion leukemias. However, the… 
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