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MLF1 gene

Known as: myeloid leukemia factor 1 variant 2, myeloid leukemia factor 1 variant 3, MYELOID LEUKEMIA FACTOR 1 
This gene plays a role in both transcriptional regulation and cell cycle arrest.
National Institutes of Health

Related topics

Related topics

5 relations
Homo sapiensMLF1 protein, humanNegative Regulation of Cell CycleTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
A cryptic submicroscopic deletion of 5’ MLF1–3’ NPM1 segment on derivative chromosome 3 in a patient with acute myeloid leukemia with t(3;5)(q25;q35)
Correspondence: Guanjun Wang, Cancer Center, the First Hospital of Jilin University, 71 Xinmin Street, Changchun, Jilin 130021… 
2015
2015
Myeloid leukemia factor 1 interfered with Bcl-XL to promote apoptosis and its function was regulated by 14-3-3
Myeloid leukemia factor 1 (MLF1) was involved in t(3;5) chromosomal rearrangement and aberrantly expressed in myelodysplastic… 
2013
2013
HLS 7 , a hemopoietic lineage switch gene homologous to the leukemia-inducing gene MLF 1
Hemopoietic lineage switching occurs when leukemic cells, apparently committed to one lineage, change and display the phenotype… 
Review
2010
Review
2010
MLF1 (myelodysplasia/myeloid leukemia factor 1)
Review on MLF1 (myelodysplasia/myeloid leukemia factor 1), with data on DNA, on the protein encoded, and where the gene is… 
2009
2009
Étude des interactions protéiques impliquant NPM-MLF1 dans la leucémie myéloïde aiguë.
Different genomic translocations are frequently associated with the development of acute myeloid leukemia (AML). Genomic… 
2008
2008
The myeloid leukemia factor interacts with COP9 signalosome subunit 3 in Drosophila melanogaster
The human myeloid leukemia factor 1 (hMLF1) gene was first identified as an NPM–hMLF1 fusion gene produced by chromosomal… 
2008
2008
MLF1 Is a Candidate Susceptibility Factor for T-AML That Induces Apoptosis in Normal Hematopoietic Cells
Treatment-related acute myeloid leukemia (t-AML) arises as a result of prior exposure to radiation, alkylator chemotherapy or… 
2006
2006
Aberrant subcellular expression of nucleophosmin and NPM-MLF1 fusion protein in acute myeloid leukaemia carrying t(3;5): A comparison with NPMc+ AML
B Falini1, B Bigerna1, A Pucciarini1, E Tiacci1,8, C Mecucci1, SW Morris2, N Bolli1, R Rosati1, S Hanissian2, Z Ma2, Y Sun2, E… 
2003
2003
Detection of NPM/MLF1 fusion in t(3;5)-positive acute myeloid leukemia and myelodysplasia.
Highly Cited
1999
Highly Cited
1999
HLS7, a hemopoietic lineage switch gene homologous to the leukemia‐inducing gene MLF1
Hemopoietic lineage switching occurs when leukemic cells, apparently committed to one lineage, change and display the phenotype… 
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