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Abstractβ-Lactam antibiotics represent the most commonly prescribed antibacterial agents. New β-lactams have been introduced… Expand Ertapenem sodium (trade name Invanz, also designated as MK-0826, MK-826 and L-749345), manufactured by Merck & Co., Inc. is a… Expand Beta-lactam antibiotics represent the most commonly prescribed antibacterial agents. New beta-lactams have been introduced… Expand Publisher Summary This chapter examines the various developments in antibacterial research. Significant effort continues to be… Expand During the last few decades, several carbapenems have been developed. The major characteristic of the newer drugs, such as MK-826… Expand ABSTRACT The activity of MK-826 was compared to the activities of cefoxitin, ceftriaxone, imipenem, and meropenem against 363… Expand After intravenous administration of MK-826, a new carbapenem antibiotic, the compound exhibited nonlinear pharmacokinetics in… Expand ABSTRACT MK-826 (formerly L-749,345), is a potent 1-β-methyl carbapenem with a long half-life and broad spectrum of activity… Expand