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MK 417

Known as: MK-417 
National Institutes of Health

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2 relations

Broader (2)

sezolamidesezolamide hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Comparison of intraocular pressure lowering by topical and systemic carbonic anhydrase inhibitors in the rabbit.
We compared the effect on intraocular pressure (IOP) of maximal doses of a topical carbonic anhydrase inhibitor (CAI) at acidic… 
1995
1995
Catalytic and inhibitor-binding properties of some active-site mutants of human carbonic anhydrase I.
Three isozyme-specific residues in the active site of human carbonic anhydrase I, Val62, His67, and His200, have been changed by… 
1992
1992
Sezolamide: Additivity to timolol twice daily
Sezolamide, a potent topical carbonic anhydrase inhibitor previously known as MK-417, was studied to determine its ocular… 
Review
1992
Review
1992
Topical carbonic anhydrase inhibitors: a new perspective in glaucoma therapy.
Oral carbonic anhydrase inhibitors have been used extensively in the treatment of all types of glaucoma. These agents reduce… 
1991
1991
Multiple-dose efficacy comparison of the two topical carbonic anhydrase inhibitors sezolamide and MK-927.
The multiple-dose twice-daily efficacy of the topical carbonic anhydrase inhibitor MK-927, a racemic compound, was compared with… 
1991
1991
Comparative tolerability of topical carbonic anhydrase inhibitor MK-927 and its S-enantiomer MK-417
A single-dose, randomised, double-masked, placebo-controlled, five-period cross-over comparative ocular tolerance study was… 
1991
1991
Dose-Dependent Pharmacokinetics of MK-417, a Potent Carbonic Anhydrase Inhibitor, in Experimental Polycythemic and Anemic Rats
MK-417 is a potent carbonic anhydrase inhibitor currently under clinical investigation as a topical ocular hypotensive agent… 
1990
1990
Dose-dependent pharmacokinetics of MK-417, a potent carbonic anhydrase inhibitor, in rabbits following single and multiple doses.
MK-417, a potent carbonic anhydrase inhibitor capable of reducing intraocular pressure after topical application, is currently… 
1990
1990
LOKALE KARBOANHYDRASEHEMMER MK-927 UND MK-417 : WIRKUNG UND VERTRAGLICHKEIT
A comparative ocular tolerance study was undertaken with the topical carbonic anhydrase inhibitor (CAI) MK-927 (1% and 2%) and… 
1990
1990
[Local carbonic anhydrase inhibitors MK-927 and Mk-417. Effect and tolerance].
A comparative ocular tolerance study was undertaken with the topical carbonic anhydrase inhibitor (CAI) MK-927 (1% and 2%) and… 
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