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MK 212

Known as: MK-212 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Serotonin-2C receptors in the basolateral nucleus of the amygdala mediate the anxiogenic effect of acute imipramine and fluoxetine administration.
A growing body of evidence indicates that facilitation of serotonin-2C receptor (5-HT2CR)-mediated neurotransmission in the… Expand
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2005
2005
Behavioral effects of systemically administered MK-212 are prevented by ritanserin microinfusion into the basolateral amygdala of rats exposed to the elevated plus-maze
RationaleAlthough 5-HT2 receptors seem to play an important role in anxiety, results from numerous studies are still highly… Expand
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Review
2004
Review
2004
Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia
Clozapine administration to schizophrenic patients was found to produce dopamine2 (D-2) and serotonin2 (5-HT2) receptor blockade… Expand
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Highly Cited
2003
Highly Cited
2003
Serotonin receptors involved in vasopressin and oxytocin secretion.
Serotonin (5-HT), 5-HT agonists, the 5-HT precursor 5-hydroxytryptophan, 5-HT-releasers and -reuptake inhibitors stimulate the… Expand
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Highly Cited
1999
Highly Cited
1999
Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells.
1. The goal of this study was to characterize the agonist pharmacology of human 5-HT2A, 5-HT2B and 5-HT2C (VSV) receptors… Expand
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Review
1998
Review
1998
Behavioral Satiety Sequence (BSS) for the Diagnosis of Drug Action on Food Intake
The Behavioral Satiety Sequence (BSS) is the name given to the orderly transitions of eating, activity grooming and resting… Expand
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Highly Cited
1997
Highly Cited
1997
Direct injection of 5-HT2A receptor agonists into the medial prefrontal cortex produces a head-twitch response in rats.
The serotonin (5-HT)(2A/2c) agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), the 5-HT2C agonist 6-chloro-2-[1… Expand
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Highly Cited
1989
Highly Cited
1989
Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl)piperazine on locomotor activity.
The piperazine-type 5-hydroxytryptamine (5-HT) agonists 1-(m-trifluoromethylphenyl)piperazine (TFMPP), 1-(m-chlorophenyl… Expand
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1988
1988
Stimulation of serum cortisol and prolactin secretion in humans by MK-212, a centrally active serotonin agonist
The effects of MK-212 [6-chloro-2-(1-piperazinyl)-pyrazine] (10, 20, and 40 mg, orally), a centrally acting serotonin (5-HT… Expand
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Highly Cited
1986
Highly Cited
1986
Thermoregulatory responses to serotonin (5-HT) receptor stimulation in the rat: Evidence for opposing roles of 5-HT2 and 5-HT1A receptors
The effects of serotonergic agonists and antagonists on the body temperatures of rats were investigated. The administration of… Expand
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