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MK-0974

Known as: MK 0974, MK0974 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

telcagepant

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Lack of hemodynamic interaction between CGRP-receptor antagonist telcagepant (MK-0974) and sumatriptan: Results from a randomized study in patients with migraine
Objective The objective of this article is to assess the effects of sumatriptan monotherapy, telcagepant monotherapy, and their… 
Review
2011
Review
2011
Telcagepant: A New Therapeutic Option for Acute Migraine
Telcagepant (MK0974) is one of several calcitonin-gene-related peptide antagonists in development as a potential treatment for… 
Review
2011
Review
2011
ACS chemical neuroscience molecule spotlight on Telcagepant (MK-0974).
Telcagepant (MK-0974) is a novel calcitonin gene-related peptide (CGRP) receptor antagonist currently undergoing clinical trials… 
Highly Cited
2010
Highly Cited
2010
Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974).
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT * Calcitonin gene-related peptide (CGRP) was first described as a potent vasodilator… 
2009
2009
A flexible and high throughput liquid chromatography-tandem mass spectrometric assay for the quantitation of telcagepant in human plasma.
Review
2009
Review
2009
Calcitonin gene-related peptide receptor antagonists for the treatment of migraine.
Review
2008
Review
2008
Inhibition of Calcitonin Gene‐Related Peptide Function: A Promising Strategy for Treating Migraine
The neuropeptide calcitonin gene‐related peptide (CGRP) is implicated in the underlying pathology of migraine. Serum levels of… 
Review
2008
Review
2008
Proinflammatory mediators and migraine pathogenesis: moving towards CGRP as a target for a novel therapeutic class
Migraine is a complex neurological disorder in which genetic and environmental factors interact. At present, frontline therapies… 
2008
2008
Calcitonin gene-related peptide (CGRP) antagonists and migraine
Three things attracted me to headache some years ago: the pathophysiology of the disorder presented to students—the vascular… 
2008
2008
Reversed-phase chiral liquid chromatography on polysaccharide-based stationary phase coupled with tandem mass spectrometry for simultaneous determination of four stereoisomers of MK-0974 in human…
  • Yang XuD. Musson
  • Journal of chromatography. B, Analytical…
  • 2008
  • Corpus ID: 35090717
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