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MGS 0039
Known as:
MGS-0039
, MGS0039
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Role of calcium, glutamate and NMDA in major depression and therapeutic application
L. Deutschenbaur
,
J. Beck
,
+6 authors
U. Lang
Progress in Neuro-psychopharmacology and…
2016
Corpus ID: 22845830
Highly Cited
2016
Highly Cited
2016
Rapid and Sustained Antidepressant Action of the mGlu2/3 Receptor Antagonist MGS0039 in the Social Defeat Stress Model: Comparison with Ketamine
C. Dong
,
Ji-chun Zhang
,
+5 authors
K. Hashimoto
International Journal of Neuropsychopharmacology
2016
Corpus ID: 3773397
Abstract Background: Similar to the N-methyl-D-aspartate receptor antagonist ketamine, the metabotropic glutamate 2/3 receptor…
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Review
2013
Review
2013
Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders
K. Hashimoto
,
B. Malchow
,
P. Falkai
,
A. Schmitt
European Archives of Psychiatry and Clinical…
2013
Corpus ID: 23693610
Severe psychiatric disorders such as schizophrenia are related to cognitive and negative symptoms, which often are resistant to…
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Highly Cited
2011
Highly Cited
2011
Involvement of the mammalian target of rapamycin signaling in the antidepressant-like effect of group II metabotropic glutamate receptor antagonists
H. Koike
,
M. Iijima
,
S. Chaki
Neuropharmacology
2011
Corpus ID: 23923192
Review
2008
Review
2008
Mood disorders: regulation by metabotropic glutamate receptors.
Andrzej Pilc
,
S. Chaki
,
G. Nowak
,
J. Witkin
Biochemical Pharmacology
2008
Corpus ID: 27826897
Highly Cited
2006
Highly Cited
2006
An mGluR2/3 antagonist, MGS0039, exerts antidepressant and anxiolytic effects in behavioral models in rats
T. Yoshimizu
,
T. Shimazaki
,
Akie Ito
,
S. Chaki
Psychopharmacology
2006
Corpus ID: 7801709
RationaleAbnormalities of glutamatergic neurotransmission have been reportedly observed in psychiatric disorders. Previously, we…
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Highly Cited
2006
Highly Cited
2006
A metabotropic glutamate 2/3 receptor antagonist, MGS0039, increases extracellular dopamine levels in the nucleus accumbens shell
J. Karasawa
,
T. Yoshimizu
,
S. Chaki
Neuroscience Letters
2006
Corpus ID: 20736438
Highly Cited
2005
Highly Cited
2005
AMPA receptor stimulation mediates the antidepressant-like effect of a group II metabotropic glutamate receptor antagonist
J. Karasawa
,
T. Shimazaki
,
N. Kawashima
,
S. Chaki
Brain Research
2005
Corpus ID: 24117168
Highly Cited
2004
Highly Cited
2004
MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity
S. Chaki
,
R. Yoshikawa
,
+9 authors
A. Nakazato
Neuropharmacology
2004
Corpus ID: 40533560
Highly Cited
2004
Highly Cited
2004
Increased cell proliferation in the adult mouse hippocampus following chronic administration of group II metabotropic glutamate receptor antagonist, MGS0039.
T. Yoshimizu
,
S. Chaki
Biochemical and Biophysical Research…
2004
Corpus ID: 2451207
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