MGCD516

Known as: Multitargeted Kinase Inhibitor MGCD516 
An orally bioavailable, receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Upon administration, multitargeted kinase… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2016
012320002016

Papers overview

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Review
2017
Review
2017
The tropomyosin receptor kinase (TRK) family includes TRKA, TRKB, and TRKC proteins, which are encoded by NTRK1, NTRK2 and NTRK3… (More)
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2017
2017
Alzheimer's disease (AD) is a complex, multifactorial disease in which different neuropathological mechanisms are likely involved… (More)
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2016
2016
A new series of 2-amino-4-oxo-6-substituted pyrrolo[2,3-d]pyrimidines, with an isosteric replacement of the side chain amide… (More)
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2016
2016
generation, multitargeted tyrosinekinase inhibitor (TKI) ponatinib has improved the outcomes of patients with treatment… (More)
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2014
2014
Pheochromocytomas and paragangliomas are neuroendocrine tumors shown to be responsive to multitargeted tyrosine kinase inhibitor… (More)
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2013
2013
Dietary phytochemicals as adjuvants have been suggested to play important roles in enhancing chemotherapeutic potential owing to… (More)
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2012
2012
UNLABELLED One of the central unanswered questions in prostate cancer research is the significance of tyrosine kinase inhibitor… (More)
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2001
2001
This study was performed to assess the feasibility of administering 1843U89, a potent, noncompetitive inhibitor of thymidylate… (More)
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2000
2000
The scheduling of antifolate antitumor agents, including the new multitargeted autofolate LY231514 (MTA), with 5-fluorouracil was… (More)
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