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MGCD516

Known as: Multitargeted Kinase Inhibitor MGCD516 
An orally bioavailable, receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Upon administration, multitargeted kinase… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Epilepsy is a chronic neurologic disorder that affects over 70 million people worldwide. Despite the availability of over 20… Expand
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Review
2017
Review
2017
&NA; The tropomyosin receptor kinase (TRK) family includes TRKA, TRKB, and TRKC proteins, which are encoded by NTRK1, NTRK2 and… Expand
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2017
2017
Alzheimer’s disease (AD) is a complex, multifactorial disease in which different neuropathological mechanisms are likely involved… Expand
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2016
2016
Sarcomas are rare but highly aggressive mesenchymal tumors with a median survival of 10–18 months for metastatic disease… Expand
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Review
2015
Review
2015
UNLABELLED The use of high-throughput next-generation sequencing techniques in multiple tumor types during the last few years has… Expand
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2013
2013
Modification of drug delivery nanomaterials with affinity molecules that facilitate targeting, has rendered a new class of… Expand
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2013
2013
Dietary phytochemicals as adjuvants have been suggested to play important roles in enhancing chemotherapeutic potential owing to… Expand
2012
2012
One of the central unanswered questions in prostate cancer research is the significance of tyrosine kinase inhibitor (TKI… Expand
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Highly Cited
2005
Highly Cited
2005
563 Background: Autocrine and paracrine signaling involving VEGFR and PDGFR are implicated in angiogenesis and proliferation of… Expand
Highly Cited
2000
Highly Cited
2000
The scheduling of antifolate antitumor agents, including the new multitargeted autofolate LY231514 (MTA), with 5-fluorouracil was… Expand
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