Skip to search formSkip to main contentSkip to account menu

MG 132

Known as: MG-132, MG132, Proteasome Inhibitor MG-132 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

benzyloxycarbonylleucyl-leucyl-leucine aldehyde

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Multiple cardiac proteasome subtypes differ in their susceptibility to proteasome inhibitors.
AIMS The proteasome is the proteolytically active core of the ubiquitin-proteasome system, which regulates vital processes and… 
Highly Cited
2006
Highly Cited
2006
Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress.
Hyperphosphorylated tau proteins accumulate in the paired helical filaments of neurofibrillary tangles seen in such tauopathies… 
Highly Cited
2006
Highly Cited
2006
Proteasome inhibitor‐induced apoptosis in human monocyte‐derived dendritic cells
Proteasome inhibitors possess potent antitumor activity against a broad spectrum of human malignancies. However, the effects of… 
Highly Cited
2003
Highly Cited
2003
Molecular Determinants of Glucocorticoid Receptor Mobility in Living Cells: the Importance of Ligand Affinity
ABSTRACT The actions of glucocorticoids are mediated by the glucocorticoid receptor (GR), which is activated upon ligand binding… 
Highly Cited
2003
Highly Cited
2003
p27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes
ABSTRACT Our studies address questions pertaining to the regulation of D cyclin-cdk4 activity, and the following results were… 
Highly Cited
2002
Highly Cited
2002
Endotoxin stress-response in cardiomyocytes: NF-κB activation and tumor necrosis factor-α expression
Although tumor necrosis factor (TNF)-α is implicated in numerous cardiac pathologies, the intracellular events leading to its… 
Highly Cited
2000
Highly Cited
2000
Role of the Cytokine-inducible SH2 Protein CIS in Desensitization of STAT5b Signaling by Continuous Growth Hormone*
Growth hormone (GH)-inducible suppressors of cytokine signaling (SOCS/CIS proteins) inhibit GH receptor (GHR) signaling to STAT5b… 
Highly Cited
2000
Highly Cited
2000
Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes.
We recently reported increased sensitivity of B-cell chronic lymphocytic leukemia (B-CLL) lymphocytes to apoptotic death… 
Highly Cited
2000
Highly Cited
2000
Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (Janus kinase-signal transducer and activator transcription factor) signalling pathways in hepatocytes: differential…
Interferons (IFNs) have been used in the treatment of viral hepatitis. However, their effectiveness is much reduced (<10%) in… 
Highly Cited
1999
Highly Cited
1999
The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells.
This study deals with the apoptotic effect exerted on human retinoblastoma Y79 cells by both sodium butyrate and an inhibitor of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)