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MG 132

Known as: MG-132, MG132, Proteasome Inhibitor MG-132 
National Institutes of Health

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Broader (1)

benzyloxycarbonylleucyl-leucyl-leucine aldehyde

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Involvement of two distinct ubiquitin E3 ligase systems for p27 degradation in corneal endothelial cells.
PURPOSE p27(Kip1) (p27) is an important regulator of G(1) progression. For cells to proliferate, p27 must undergo proteolysis… 
2008
2008
Manganese chloride-induced G0/G1 and S phase arrest in A549 cells.
Highly Cited
2007
Highly Cited
2007
Sperm proteasomes are responsible for the acrosome reaction and sperm penetration of the vitelline envelope during fertilization of the sea urchin Pseudocentrotus depressus.
Highly Cited
2006
Highly Cited
2006
RNA Polymerase II Blockage by Cisplatin-damaged DNA
The consequences of human RNA polymerase II (pol II) arrest at the site of DNA damaged by cisplatin were studied in whole cells… 
Highly Cited
2006
Highly Cited
2006
The Three-Substituted Indolinone Cyclin-Dependent Kinase 2 Inhibitor 3-[1-(3H-Imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one (SU9516) Kills Human Leukemia Cells via Down…
Mechanisms of lethality of the three-substituted indolinone and putatively selective cyclin-dependent kinase (CDK)2 inhibitor 3… 
2005
2005
Evidence for proteasomal degradation of Kv1.5 channel protein.
2005
2005
Proteasome comprising a β1 inducible subunit acts as a negative regulator of NADPH oxidase during elicitation of plant defense reactions
Highly Cited
2004
Highly Cited
2004
Green Tea Polyphenol and Curcumin Inversely Regulate Human Involucrin Promoter Activity via Opposing Effects on CCAAT/Enhancer-binding Protein Function*
Antioxidants are important candidate agents for the prevention of disease. However, the possibility that different antioxidants… 
Highly Cited
2002
Highly Cited
2002
Proteasome inhibitors stimulate interleukin-8 expression via Ras and apoptosis signal-regulating kinase-dependent extracellular signal-related kinase and c-Jun N-terminal kinase activation.
In this study, we investigated the effects of proteasome inhibibors (MG132 and lactacystin) on interleukin (IL)-8 induction. In… 
Highly Cited
1997
Highly Cited
1997
Degradation of E2A Proteins through a Ubiquitin-conjugating Enzyme, UbcE2A*
The helix-loop-helix E2A proteins (E12 and E47) govern cellular growth and differentiation. To identify binding partners that… 
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