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MF59 oil emulsion

Known as: MF59 
National Institutes of Health

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Broader (4)

Immunologic AdjuvantsPolysorbatesSqualeneSurface-Active Agents

Papers overview

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Highly Cited
2017
Highly Cited
2017
Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake
Vaccine responses are initiated in vaccine-draining lymph nodes and depend on the efficiency by which adjuvants influence antigen… 
Review
2016
Review
2016
Vaccine development: From concept to early clinical testing.
Highly Cited
2015
Highly Cited
2015
Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus
Middle East respiratory syndrome (MERS), an emerging infectious disease caused by MERS coronavirus (MERS-CoV), has garnered… 
Highly Cited
2008
Highly Cited
2008
The Adjuvants Aluminum Hydroxide and MF59 Induce Monocyte and Granulocyte Chemoattractants and Enhance Monocyte Differentiation toward Dendritic Cells1
Aluminum hydroxide (alum) and the oil-in-water emulsion MF59 are widely used, safe and effective adjuvants, yet their mechanism… 
Highly Cited
2003
Highly Cited
2003
Boosting immunity to influenza H5N1 with MF59-adjuvanted H5N3 A/Duck/Singapore/97 vaccine in a primed human population.
Review
2003
Review
2003
MF59-adjuvanted vaccines: increased immunogenicity with an optimal safety profile
The need to enhance the immunogenicity of purified subunit antigens has prompted the development of several new adjuvants… 
Highly Cited
1999
Highly Cited
1999
Distribution of adjuvant MF59 and antigen gD2 after intramuscular injection in mice.
Highly Cited
1998
Highly Cited
1998
Dendritic cells internalize vaccine adjuvant after intramuscular injection.
Vaccine adjuvants help antigens elicit rapid, potent, and long-lasting immune responses. The lack of understanding of the… 
Review
1995
Review
1995
MF59. Design and evaluation of a safe and potent adjuvant for human vaccines.
MF59 is a safe, practical, and potent adjuvant for use with human vaccines. The formulation is easily manufactured, may be… 
Highly Cited
1994
Highly Cited
1994
Systemic cytokine profiles in BALB/c mice immunized with trivalent influenza vaccine containing MF59 oil emulsion and other advanced adjuvants.
We have studied serum cytokine profiles in BALB/c mice after immunization with influenza vaccine alone or combined with the… 
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