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MEIS1 protein, human

Known as: MEIS1 Homeobox Protein, Homeobox Protein Meis1, MEIS1 Homolog 
MEIS1 Homeobox Protein Homeobox protein Meis1 (390 aa, ~43 kDa) is encoded by the human MEIS1 gene. This protein plays a role in transcriptional… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Gene expression is regulated by transcription factors (TFs), proteins that recognize short DNA sequence motifs. Such sequences… Expand
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Highly Cited
2013
Highly Cited
2013
The neonatal mammalian heart is capable of substantial regeneration following injury through cardiomyocyte proliferation. However… Expand
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Highly Cited
2007
Highly Cited
2007
Oncogenic mutations of the MLL histone methyltransferase confer an unusual ability to transform non-self-renewing myeloid… Expand
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Highly Cited
2005
Highly Cited
2005
Homeodomain proteins of the Meis subfamily are expressed dynamically in several organs during embryogenesis and exert potent… Expand
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Highly Cited
2004
Highly Cited
2004
Meis1 and Hoxa9 expression is upregulated by retroviral integration in murine myeloid leukemias and in human leukemias carrying… Expand
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Highly Cited
2001
Highly Cited
2001
Rearrangements of the human ALL-1 gene are frequently encountered in acute lymphocytic leukemias (ALL) and acute myeloid… Expand
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Highly Cited
2001
Highly Cited
2001
Complex genetic and biochemical interactions between HOX proteins and members of the TALE (i.e., PBX and MEIS) family have been… Expand
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Highly Cited
1999
Highly Cited
1999
Aberrant activation of the HOX, MEIS, and PBX homeodomain protein families is associated with leukemias, and retrovirally driven… Expand
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Highly Cited
1997
Highly Cited
1997
E2a-Pbx1 is a chimeric transcription factor oncoprotein produced by the t(1;19) translocation in human pre-B cell leukemia. Class… Expand
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Highly Cited
1995
Highly Cited
1995
Leukemia results from the accumulation of multiple genetic alterations that disrupt the control mechanisms of normal growth and… Expand
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