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MEF2A gene
Known as:
MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
, MEF2A
, RSRFC9
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This gene plays a role in transcriptional regulation, muscle development and transcriptional responses to stress and growth factors.
National Institutes of Health
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Related topics
Related topics
7 relations
Homo sapiens
Organogenesis
Transcription, Genetic
Transcriptional Regulation
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MEF2A wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Inhibition of MEF2A prevents hyperglycemia-induced extracellular matrix accumulation by blocking Akt and TGF-β1/Smad activation in cardiac fibroblasts.
Xue-ying Chen
,
Guo-liang Liu
,
+6 authors
Ming-Xiang Zhang
International Journal of Biochemistry and Cell…
2015
Corpus ID: 40532624
Highly Cited
2005
Highly Cited
2005
Multiple reaction monitoring as a method for identifying protein posttranslational modifications.
D. M. Cox
,
F. Zhong
,
M. Du
,
E. Duchoslav
,
T. Sakuma
,
J. C. McDermott
Journal of Biomolecular Techniques
2005
Corpus ID: 11087933
The activity of many transcriptional regulators is significantly altered by posttranslational modifications of specific sites…
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Highly Cited
2005
Highly Cited
2005
MEF2A sequence variants and coronary artery disease: a change of heart?
D. Altshuler
,
J. Hirschhorn
Journal of Clinical Investigation
2005
Corpus ID: 11859175
Rare mutations in MEF2A have been proposed as a cause of coronary artery disease (CAD) and myocardial infarction (MI). In this…
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2005
2005
Assessment of MEF2A mutations in myocardial infarction in Japanese patients.
Kazuaki Kajimoto
,
K. Shioji
,
+4 authors
N. Iwai
Circulation Journal
2005
Corpus ID: 22174739
BACKGROUND Recently, a mutation in the human MEF2A gene was reported to be responsible for an autosomal dominant form of coronary…
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2004
2004
ERK5 is targeted to myocyte enhancer factor 2A (MEF2A) through a MAPK docking motif.
D. Barsyte-Lovejoy
,
A. Galanis
,
A. Clancy
,
A. Sharrocks
Biochemical Journal
2004
Corpus ID: 42641090
One critical component in determining the specificity, and efficiency of MAPK (mitogen-activated protein kinase) substrate…
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Highly Cited
1997
Highly Cited
1997
The MEF2A 3' untranslated region functions as a cis-acting translational repressor
B. Black
,
J. Lu
,
E. Olson
Molecular and Cellular Biology
1997
Corpus ID: 23288939
Myocyte enhancer factor 2 (MEF2) proteins serve as important muscle transcription factors. In addition, MEF2 proteins have been…
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Highly Cited
1996
Highly Cited
1996
The expression of MEF2 genes is implicated in CNS neuronal differentiation.
X. Lin
,
S. Shah
,
R. F. Bulleit
Brain Research. Molecular Brain Research
1996
Corpus ID: 21346615
Highly Cited
1995
Highly Cited
1995
DNA binding specificity determinants in MADS-box transcription factors
S. Nurrish
,
R. Treisman
Molecular and Cellular Biology
1995
Corpus ID: 11781816
The MADS box is a conserved sequence motif found in the DNA binding domain of a family of transcription factors which possess…
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1995
1995
MEF2 proteins, including MEF2A, are expressed in both muscle and non-muscle cells.
E. Dodou
,
D. Sparrow
,
T. Mohun
,
R. Treisman
Nucleic Acids Research
1995
Corpus ID: 36137606
The MEF2 proteins are involved in regulation of many muscle specific genes. Although MEF2 RNAs encoding the MEF2A and MEF2D…
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Highly Cited
1993
Highly Cited
1993
The identification of elements determining the different DNA binding specificities of the MADS box proteins p67SRF and RSRFC4.
A. Sharrocks
,
F. von Hesler
,
P. Shaw
Nucleic Acids Research
1993
Corpus ID: 15158776
The human transcription factors p67SRF and RSRFC4 recognise similar but distinct binding sites which are found in the promoters…
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