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MED1 gene

Known as: DRIP205, TRAP220, MED1 
This gene plays a role in the transcriptional activation of target genes. It is involved in embryonic fibroblast differentiation and normal… 
National Institutes of Health

Related topics

Related topics

4 relations
Homo sapiensTranscriptional ActivationTranscriptional Regulationthyroid hormone receptor associated protein 220

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
1α,25‐dihydroxy vitamin D3‐enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1α,25‐dihydroxy vitamin…
Binding of 1α,25‐dihydroxy vitamin D3 to the C‐terminal ligand‐binding domain (LBD) of its receptor (VDR) induces a… 
2003
2003
MED1: A central molecule for maintenance of genome integrity and response to DNA damage
Maintaining genome integrity is a dynamic process that involves many different cellular pathways, including methylation… 
Highly Cited
2002
Highly Cited
2002
Deletion of the Cancer-amplified Coactivator AIB3 Results in Defective Placentation and Embryonic Lethality*
The amplified in breast cancer-3 (AIB3, ASC-2, RAP250, PRIP, TRBP, NRC, or NcoA6) gene is characterized as a cancer-amplified… 
2002
2002
Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205.
Nuclear receptors (NR) activate transcription by interacting with several different coactivator complexes, primarily via LXXLL… 
2001
2001
Reconstruction of Escherichia coli mrcA (PBP 1a) Mutants Lacking Multiple Combinations of Penicillin Binding Proteins
ABSTRACT Previously, we constructed a set of mutants from which eight penicillin binding protein (PBP) genes were deleted in 192… 
Highly Cited
2000
Highly Cited
2000
Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain.
The human DNA repair protein MED1 (also known as MBD4) was isolated as an interactor of the mismatch repair protein MLH1 in a… 
Highly Cited
1999
Highly Cited
1999
The Med1 subunit of the yeast mediator complex is involved in both transcriptional activation and repression.
The mediator complex is essential for regulated transcription in vitro. In the yeast Saccharomyces cerevisiae, mediator comprises… 
Highly Cited
1999
Highly Cited
1999
Competition between Thyroid Hormone Receptor-associated Protein (TRAP) 220 and Transcriptional Intermediary Factor (TIF) 2 for Binding to Nuclear Receptors
Transcriptional activation by nuclear receptors (NRs) involves the concerted action of coactivators, chromatin components, and… 
Highly Cited
1987
Highly Cited
1987
A second regulatory gene, blaR1, encoding a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis
A second regulatory locus (blaR1) required for the induction of beta-lactamase synthesis in Bacillus licheniformis 749 was cloned… 
1983
1983
Penicillin-binding proteins in Bacteroides fragilis.
The penicillin binding proteins (PBSs) of Bacteroides fragilis, a clinically important Gram-negative rod, were studied. Four PBPs… 
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