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ME3738

 
National Institutes of Health

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Related topics

2 relations

Broader (1)

Oleanolic Acid
analogs & derivatives

Papers overview

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2016
2016
Antiproliferative effect of ME3738, a derivative of soyasapogenol, on hepatocellular carcinoma cell lines in vitro and in vivo.
Soyasapogenol, an aglycon of soyasaponin, ameliorates liver injury induced by concanavalin A in mice. A derivative of… Expand
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2014
2014
Clinical efficacy of combination therapy with ME3738 and pegylated interferon-alpha-2a in patients with hepatitis C virus genotype 1.
AIM ME3738, a derivative of soyasapogenol B, enhances the anti-hepatitis C virus (HCV) effect of interferon in an in vitro… Expand
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2011
2011
ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo.
BACKGROUND & AIMS ME3738 (22β-methoxyolean-12-ene-3β, 24-diol), a derivative of soyasapogenol B, attenuates liver disease in… Expand
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2008
2008
Preventive effects of ME3738 on hepatic fibrosis induced by bile duct ligation in rats.
AIM The aim of this study was to examine the preventive effects of ME3738 on hepatic fibrosis induced by bile duct ligation (BDL… Expand
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2008
2008
Hepatitis C virus replication is inhibited by 22beta-methoxyolean-12-ene-3beta, 24(4beta)-diol (ME3738) through enhancing interferon-beta.
UNLABELLED A derivative of soyasapogenol, 22beta-methoxyolean-12-ene-3beta, 24(4beta)-diol (ME3738), ameliorates liver injury… Expand
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2008
2008
Preventive effects of ME3738 on hepatic fibrosis induced by bile duct ligation in rats
 
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2007
2007
Effect of the inducer of interleukin-6 (ME3738) on rat liver treated with ethanol.
BACKGROUND Recently, ME3738, a derivative of soyasapogenol B, was developed as an inducer of interleukin (IL)-6. It has been… Expand
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2007
2007
ME3738 protects against lithocholic acid-induced hepatotoxicity, which is associated with enhancement of biliary bile acid and cholesterol output.
ME3738 (22beta-methoxyolean-12-ene-3beta, 24(4beta)-diol), a derivative of soyasapogenol, attenuates liver disease in several… Expand
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2006
2006
Protective effects of alpha1-acid glycoprotein and serum amyloid A on concanavalin A-induced liver failure via interleukin-6 induction by ME3738.
We examined whether the 22beta-methoxyolean-12-ene-3beta,24(4beta)-diol (ME3738)-mediated selective induction of interleukin-6… Expand
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2003
2003
ME3738 protects from concanavalin A-induced liver failure via an IL-6-dependent mechanism.
ME3738 is a new compound that attenuates liver disease in several models of acute and chronic liver inflammation. We used the… Expand
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