MDX-H210 antibody

Known as: 520C9xH22 bispecific antibody, bispecific antibody 520C9xH22, bispecific antibody 520C9x22 
A humanized bivalent antibody directed against both cytotoxic effector cells expressing Fc gamma receptor type I (Fc gammaRI, or CD64) and HER2/neu… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
05101519792017

Papers overview

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Highly Cited
2012
Highly Cited
2012
The prevalence of ErbB2 amplification in breast cancer has resulted in the heavy pursuit of ErbB2 as a therapeutic target… (More)
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Highly Cited
2010
Highly Cited
2010
We have earlier shown that antisense morpholino oligomers are able to restore dystrophin expression by systemic delivery in body… (More)
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2004
2004
Unconjugated monoclonal antibodies have emerged as important therapeutic agents for selected malignancies. One mechanism by which… (More)
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2003
2003
A phase I study of the bispecific antibody MDX-H210 in combination with granulocyte colony-stimulating factor (G-CSF) was… (More)
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Highly Cited
2000
Highly Cited
2000
Although bispecific antibodies directed against malignant lymphoma have been shown to be effective in vitro and in vivo, extended… (More)
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2000
2000
Recombinant adenoviral vectors are attractive in the context of cancer gene therapy because they are capable of delivering genes… (More)
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Highly Cited
1999
Highly Cited
1999
Important therapeutic applications of genetically modified dendritic cells (DC) have been proposed; however, current vector… (More)
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Highly Cited
1999
Highly Cited
1999
We have developed a system for the targeted delivery of adeno–associated virus (AAV) vectors. Targeting is achieved via a… (More)
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Highly Cited
1995
Highly Cited
1995
PURPOSE MDX-210 is a bispecific antibody that binds simultaneously to type I Fc receptors for immunoglobulin G (IgG) (Fc gamma RI… (More)
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Highly Cited
1992
Highly Cited
1992
DYSTROPHIN is associated with a complex of muscle membrane (sarcolemmal) glycoproteins that provide a linkage to the… (More)
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