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MDV 3100
Known as:
ASP9785
, MDV-3100
, MDV3100
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (1)
Phenylthiohydantoin
analogs & derivatives
Narrower (1)
enzalutamide
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
The emergence of extracellular vesicles in urology: fertility, cancer, biomarkers and targeted pharmacotherapy
A. Tompkins
,
D. Chatterjee
,
+5 authors
J. Renzulli
Journal of Extracellular Vesicles
2015
Corpus ID: 16698964
Extracellular vesicles (EV) are small membrane-bound vesicles enriched in a selective repertoire of mRNA, miRNA, proteins and…
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2013
2013
Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100.
D. End
,
A. Molina
,
M. Todd
,
M. Meyers
Cancer Research
2013
Corpus ID: 207600421
We read with interest the report from Richards and colleagues ([1][1]) on the potential interactions of abiraterone, eplerenone…
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Review
2013
Review
2013
Castration resistant prostate cancer (CRPC): state of the art, perspectives and new challenges.
F. Massari
,
F. Maines
,
+5 authors
G. Tortora
Anti-Cancer Agents in Medicinal Chemistry
2013
Corpus ID: 9533739
The rapid approval of several novel agents has given prostate cancer patients and their treating physicians many new and…
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Review
2012
Review
2012
Association of Baseline Corticosteroid with Outcomes in a Multivariate Analysis of the Phase 3 Affirm Study of Enzalutamide (ENZA), An Androgen Receptor Signaling Inhibitor (ARSI)
H. Scher
,
K. Fizazi
,
+7 authors
J. Bono
2012
Corpus ID: 220740634
Review
2012
Review
2012
Current and emerging treatments in the management of castration-resistant prostate cancer
D. Shapiro
,
Basir U. Tareen
Expert Review of Anticancer Therapy
2012
Corpus ID: 29229044
Historically, patients diagnosed with castration-resistant prostate cancer (CRPC) have had poor survival rates. In recent years…
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Review
2012
Review
2012
Putting the brakes on continued androgen receptor signaling in castration-resistant prostate cancer
A. Eichholz
,
R. Ferraldeschi
,
G. Attard
,
J. Bono
Molecular and Cellular Endocrinology
2012
Corpus ID: 5385156
2012
2012
In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancer.
Howard C. Shen
,
K. Shanmugasundaram
,
+5 authors
A. C. Rigby
Molecular Endocrinology
2012
Corpus ID: 24950622
Previously available androgen receptor (AR) antagonists (bicalutamide, flutamide, and nilutamide) have limited activity against…
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2011
2011
MDV3100 effects on androgen receptor (AR) signaling and bone marrow testosterone concentration modulation: Apreliminary report.
E. Efstathiou
,
M. Titus
,
+8 authors
C. Logothetis
Journal of Clinical Oncology
2011
Corpus ID: 42907449
4501 Background: "Intracrine" androgen signaling is linked to castrate-resistant prostate cancer (CRPC) and a "credentialed…
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Review
2011
Review
2011
Clinical trial update and novel therapeutic approaches for metastatic prostate cancer.
R. Larsson
,
N. Mongan
,
+5 authors
J. Persson
Current Medicinal Chemistry
2011
Corpus ID: 9447929
Recurrent prostate cancer (PCa) remains a major clinical challenge. Invasive and metastatic PCa lesions often exhibit a partial…
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Review
2011
Review
2011
Broadening horizons in medical management of prostate cancer
S. Niraula
,
I. Tannock
Acta oncologica
2011
Corpus ID: 8208747
Abstract Hormonal therapy. Testosterone suppression achieved either medically or surgically is the standard initial treatment for…
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