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MDL 646

Known as: MDL-646 
 
National Institutes of Health

Papers overview

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1987
1987
MDL 646 is a 16-methyl-16-methoxy PGE analog with gastric antisecretory and cytoprotective activity in rats following oral… Expand
1987
1987
The effects of single doses of 800 micrograms and 1200 micrograms of the new alprostadil analogue (prostaglandin E1 16-methyl-16… Expand
1986
1986
The synthesis of the pure diastereoisomer of 16-methoxy-16-methyl-PGF2 alpha, -PGE2, and -PGE1 is described. The absolute… Expand
1986
1986
The influence on gastroduodenal mucosa of indomethacin (50 mg t.i.d.) administration for 6 days was investigated in 7 healthy… Expand
1984
1984
MDL-646, 11,15-dihydroxy-16-methyl-16-methoxy-9-oxo- prost -13-en-1-oic acid methyl ester, is one of the most active members of a… Expand
1984
1984
The gastric protection, diarrheogenic and arterial hypotensive effects of MDL-646, a PGE1 derivative, have been studied in rats… Expand
1983
1983
The new synthetic prostaglandin 11,15-dihydroxy-16-methyl-16-methoxy-9-oxo-prost-13-en-1-oic acid,methyl ester (8 alpha,11 alpha… Expand
1983
1983
Compound marked MDL 646, a synthetic prostaglandin belonging to the 16-methyl-16-methoxy PGE1 series was tested for its motor… Expand