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MCM4 gene

Known as: CDC54, MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 4, MGC33310 
This gene plays a role in the cell cycle control of DNA replication.
National Institutes of Health

Related topics

Related topics

7 relations
ATP HydrolysisDNA ReplicationMCM4 protein, humanMinichromosome Maintenance Complex Component 4

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MCM4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Integrated analysis of key microRNAs /TFs /mRNAs/ in HPV-positive cervical cancer based on microRNA sequencing and bioinformatics analysis.
2015
2015
G364R mutation of MCM4 detected in human skin cancer cells affects DNA helicase activity of MCM4/6/7 complex.
A number of gene mutations are detected in cells derived from human cancer tissues, but roles of these mutations in cancer cell… 
2015
2015
c-ETS transcription factors play an essential role in the licensing of human MCM4 origin of replication.
Highly Cited
2007
Highly Cited
2007
Identification and Characterization of a Novel Component of the Human Minichromosome Maintenance Complex
ABSTRACT Minichromosome maintenance (MCM) complex replicative helicase complexes play essential roles in DNA replication in all… 
2007
2007
Genetic Screen for Chromosome Instability in Mice: Mcm4 and Breast Cancer
We recently isolated a hypomorphic mutation of Mcm4 in a phenotype-based screen for chromosome instability in mice. This mutation… 
2002
2002
Different phenotypes in vivo are associated with ATPase motif mutations in Schizosaccharomyces pombe minichromosome maintenance proteins.
The six conserved MCM proteins are essential for normal DNA replication. They share a central core of homology that contains… 
2001
2001
Gene expression profile in BALB/c‐3T3 cells transformed with beryllium sulfate
Differential gene expression was studied to understand the potential molecular mechanism responsible for cell transformation and… 
1998
1998
Evidence for different MCM subcomplexes with differential binding to chromatin in Xenopus.
MCM proteins are molecular components of the DNA replication licensing system in Xenopus. These proteins comprise a conserved… 
Review
1996
Review
1996
Coordinating DNA replication with cell division: current status of the licensing concept.
The replication of the genetic material during cell doubling is regulated at three apparently distinct levels. In the eukaryote… 
1991
1991
Molecular cloning of DNA from a sorted human minichromosome.
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