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MCM2 gene

Known as: MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 2, MITOTIN, CELL DIVISION CYCLE-LIKE 1 
This gene plays a role in the initiation of DNA replication. It is also involved in cell cycle control and cell proliferation.
National Institutes of Health

Related topics

Related topics

7 relations
Cell divisionDNA ReplicationMCM2 protein, humanMinichromosome Maintenance Complex Component 2

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MCM2 wt Allele

Papers overview

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Highly Cited
2015
Highly Cited
2015
PTEN Controls the DNA Replication Process through MCM2 in Response to Replicative Stress.
Highly Cited
2012
Highly Cited
2012
Integrating gene expression and protein-protein interaction network to prioritize cancer-associated genes
To understand the roles they play in complex diseases, genes need to be investigated in the networks they are involved in… 
Highly Cited
2008
Highly Cited
2008
Minichromosome maintenance protein 7 in colorectal cancer: implication of prognostic significance.
Minichromosome maintenance (MCM) proteins are essential components for DNA replication, and also prognostic markers for various… 
2006
2006
Novel markers of cell kinetics to evaluate progression from cirrhosis to hepatocellular carcinoma
Abstract: Background: We investigated cell cycle kinetics of nodular lesions in cirrhosis to differentiate hepatocellular… 
Highly Cited
2002
Highly Cited
2002
Expression of Minichromosome Maintenance 2 (MCM2), Ki-67, and Cell-Cycle-Related Molecules, and Apoptosis in the Normal-Dysplasia-Carcinoma Sequence of the Oral Mucosa
Objective: We examined cell cycle and cell death biomarker trends with the normal-dysplasia-carcinoma sequence of the oral… 
Highly Cited
2001
Highly Cited
2001
Replication Factors MCM2 and ORC1 Interact with the Histone Acetyltransferase HBO1*
The minichromosome maintenance (MCM) proteins, together with the origin recognition complex (ORC) proteins and Cdc6, play an… 
1997
1997
Mutational analysis of Cdc19p, a Schizosaccharomyces pombe MCM protein.
The cdc19+ gene encodes an essential member of the MCM family of replication proteins in Schizosaccharomyces pombe. We have… 
Highly Cited
1996
Highly Cited
1996
Mouse MCM proteins: complex formation and transportation to the nucleus
Background: The members of the MCM protein family, including MCM2, MCM3, Cdc21, CDC46, Mis5 and CDC47, are considered to be… 
Highly Cited
1994
Highly Cited
1994
A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division.
Molecular cloning and characterisation of a human nuclear protein designated BM28 is reported. On the amino acid level this 892… 
Highly Cited
1984
Highly Cited
1984
Temperature-sensitive lethal mutations on yeast chromosome I appear to define only a small number of genes.
A method was developed for isolating large numbers of mutations on chromosome I of the yeast Saccharomyces cerevisiae. A strain… 
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