MCM2 protein, human

Known as: Mitotin, minichromosome maintenance protein 2, human, BM28 protein, human 
DNA replication licensing factor MCM2 (904 aa, ~102 kDa) is encoded by the human MCM2 gene. This protein plays a role in cell cycle regulation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
0204019892017

Papers overview

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Highly Cited
2010
Highly Cited
2010
MCM2-7 proteins provide essential helicase functions in eukaryotes at chromosomal DNA replication forks. During the G1 phase of… (More)
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Highly Cited
2009
Highly Cited
2009
The licensing of eukaryotic DNA replication origins, which ensures once-per-cell-cycle replication, involves the loading of six… (More)
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Highly Cited
2009
Highly Cited
2009
The eukaryotic replisome is a crucial determinant of genome stability, but its structure is still poorly understood. We found… (More)
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Highly Cited
2009
Highly Cited
2009
During pre-replication complex (pre-RC) formation, origin recognition complex (ORC), Cdc6, and Cdt1 cooperatively load the 6… (More)
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Highly Cited
2008
Highly Cited
2008
The six main minichromosome maintenance proteins (Mcm2-7), which presumably constitute the core of the replicative DNA helicase… (More)
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Highly Cited
2007
Highly Cited
2007
In late mitosis and early G1, Mcm2-7 complexes are loaded onto DNA to license replication origins for use in the upcoming S phase… (More)
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Highly Cited
2002
Highly Cited
2002
Cdt1 is essential for loading Mcm2-7 proteins into prereplicative complexes (pre-RCs) during replication licensing and has been… (More)
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Highly Cited
2000
Highly Cited
2000
Little is known about the DNA helicases required for the elongation phase of eukaryotic chromosome replication. Minichromosome… (More)
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Highly Cited
1997
Highly Cited
1997
The initiation of DNA synthesis is an important cell cycle event that defines the beginning of S phase. This critical event… (More)
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Highly Cited
1995
Highly Cited
1995
We have recently cloned and characterized a human member (BM28) of the MCM2-3-5 family of putative relication factors (Todorov, I… (More)
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