Skip to search formSkip to main contentSkip to account menu

MCI 826

Known as: Butanoic acid, 2,2-diethyl-4-((3-(2-(4-(1-methylethyl)-2-thiazolyl)ethenyl)phenyl)amino)-4-oxo-, (E)-, MCI-826 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Thiazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Cysteinyl leukotriene‐dependent interleukin‐5 production leading to eosinophilia during late asthmatic response in guinea‐pigs
Background Allergic airway eosinophilia is suppressed by cysteinyl leukotriene (CysLT) receptor (CysLT1 receptor) antagonists in… 
1994
1994
Pharmacological profile of the novel, potent and selective peptide leukotriene antagonist (E)-2,2-diethyl-3'-[2-[2-(4-isopropyl)thiazolyl]ethenyl]succinanilic acid.
In this report, the in vitro and in vivo pharmacological profile of MCI-826 ((E)-2,2-diethyl-3'-[2-[2-(4-isopropyl) thiazolyl… 
1993
1993
Pharmacological model for airway hypersensitivity produced by propranolol and reserpine in guinea pigs.
1993
1993
Leukotriene receptors in the skin of rats differ from those of mouse skin or rat stomach strip.
1993
1993
Important role of peptide leukotrienes (p-LTs) in the resting tonus of isolated human bronchi.
The quality of the resting tonus in isolated human bronchi was investigated using a peptide leukotriene (p-LT) antagonist, a 5… 
Review
1993
Review
1993
[Resting tonus of isolated airway smooth muscles].
  • S. KohnoK. Ohata
  • Nihon yakurigaku zasshi. Folia pharmacologica…
  • 1993
  • Corpus ID: 9969729
The regulation of airway caliber is important for supporting the physiological respiratory function and is considered to be… 
1992
1992
Development of an animal model of late asthmatic response in guinea pigs and effects of anti-asthmatic drugs.
1992
1992
MCI-826 is a potent and selective antagonist of peptide leukotrienes (p-LTs) and has characteristics distinctive from those of FPL 55712.
Antagonistic effects of a newly synthesized compound, (E)-2,2-diethyl-3'-[2-[2-(4-isopropyl)thiazolyl]ethenyl]succinanilic… 
1992
1992
Leukotriene receptors in the skin of rats differ from those of mouse skin or rat stomach strip.
1992
1992
Significant role of peptide leukotrienes (p-LTs) in the antigen-induced contractions of human and guinea pig lung parenchymas and bronchi or tracheas in vitro.
Chemical mediators responsible for the antigen-induced contractions of isolated, passively sensitized human and guinea pig lung… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)