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MC4R gene

Known as: MC4R, MCR RECEPTOR, MELANOCORTIN 4 RECEPTOR 
 
National Institutes of Health

Papers overview

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2015
2015
Single gene mutations leading to severe obesity have so far been identified in 3‐5% cases in European populations. However… Expand
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Highly Cited
2012
Highly Cited
2012
BackgroundRecent genome wide association studies (GWAS) and previous positional linkage studies have identified more than 50… Expand
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Highly Cited
2011
Highly Cited
2011
Obesity may be viewed as a state of chronic low-grade inflammation that participates in the development of the metabolic syndrome… Expand
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Highly Cited
2011
Highly Cited
2011
CONTEXT Melanocortin receptor 4 (MC4R) deficiency is characterized by increased linear growth greater than expected for the… Expand
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Highly Cited
2009
Highly Cited
2009
Genome-wide association scans recently identified common polymorphisms, in intron 1 of FTO and 188 kb downstream MC4R, that… Expand
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Highly Cited
2009
Highly Cited
2009
There is evidence that the obesity phenotype in the Caucasian populations is associated with variations in several genes… Expand
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Highly Cited
2009
Highly Cited
2009
Melanocortin receptor agonists act in the brain to regulate food intake and body weight and, independently of these actions… Expand
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Highly Cited
2003
Highly Cited
2003
Heterozygous mutations in the coding sequence of the serpentine melanocortin 4 receptor (MC4R) are the most frequent genetic… Expand
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Highly Cited
2002
Highly Cited
2002
The prevalence of mutations within and in the flanking regions of the gene encoding the melanocortin 4 receptor was investigated… Expand
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Highly Cited
1990
Highly Cited
1990
The stability of methicillin resistance (Mcr) in three independent clinical isolates, MR108, MR6, and MR61, of methicillin… Expand
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