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MAP3K1 wt Allele

Known as: MAPKKK1, MEKK1, Mitogen-Activated Protein Kinase Kinase Kinase 1 wt Allele 
Human MAP3K1 wild-type allele is located in the vicinity of 5q11.2 and is approximately 82 kb in length. This allele, which encodes mitogen-activated… 
National Institutes of Health

Related topics

Related topics

32 relations
5q11.2Angiotensin II Signaling PathwayB Cell Receptor Signaling PathwayCD40L Signaling Pathway

Broader (1)

MAP3K1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
SAK-HV Decreases the Self-Ubiquitination of MEKK1 to Promote Macrophage Proliferation via MAPK/ERK and JNK Pathways
SAK-HV is an anti-atherosclerosis recombinant fusion protein developed by our lab. Our study determined that SAK-HV promoted… 
2007
2007
Genetic interaction and phenotypic analysis of the Arabidopsis MAP kinase pathway mutations mekk1 and mpk4 suggests signaling pathway complexity
2006
2006
Human glutathione S-transferase P1 suppresses MEKK1-mediated apoptosis by regulating MEKK1 kinase activity in HEK293 cells.
2006
2006
Cholecystokinin 1 receptor modulates the MEKK1‐induced c‐Jun trans‐activation: structural requirements of the receptor
In cells overexpressing active MEKK1 to enhance c‐Jun trans‐activation, expression of rat cholecystokinin 1 receptor increased… 
2003
2003
The kinase domain of MEKK1 induces apoptosis by dysregulation of MAP kinase pathways.
2002
2002
MEKK1 induces c-Jun complexes that act as negative regulators for cell survival and proliferation of HCC cells.
c-Jun has a variety of functions including proliferation, differentiation and death. c-Jun is specifically phosphorylated by c… 
2001
2001
Role of receptor-interacting protein in tumor necrosis factor-alpha -dependent MEKK1 activation.
Receptor-interacting protein (RIP), a death domain serine/threonine kinase, has been shown to play a critical role in tumor… 
2000
2000
MEKK4 Mediates Differentiation in Response to Retinoic Acid via Activation of c-Jun N-terminal Kinase in Rat Embryonal Carcinoma P19 Cells*
Differentiation of P19 embryonal carcinoma cells in response to the morphogen retinoic acid is regulated by Gα12/13 and is… 
2000
2000
Cisplatin-resistance involves the defective processing of MEKK1 in human ovarian adenocarcinoma 2008/C13 cells.
Cisplatin has been widely used as a chemotherapeutic agent to treat different types of tumors. However, its use is limited by the… 
1998
1998
hUBC9 associates with MEKK1 and type I TNF-alpha receptor and stimulates NFkappaB activity.
hUBC9, an E2 ubiquitin conjugating enzyme, was identified by yeast two-hybrid screening and coprecipitation studies to interact… 
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