M Protein, multiple myeloma

Known as: M-Protein, Paraprotein, M Proteins 
A protein complex comprised of two heavy chains and two light chains. Monoclonal immunoglobulin (M protein) is found in abundance in patients who… (More)
National Institutes of Health

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6 relations
AntibodiesImmune System ProcessesImmune responseMonoclonal Protein Measurement
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Broader (1)

Myeloma Proteins

Papers overview

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Highly Cited
2013
Highly Cited
2013
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
Most human coronaviruses cause mild upper respiratory tract disease but may be associated with more severe pulmonary disease in… (More)
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Highly Cited
2007
Highly Cited
2007
Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells.
Plasma cells producing high levels of paraprotein are dependent on the unfolded protein response (UPR) and chaperone proteins to… (More)
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Highly Cited
2007
Highly Cited
2007
Type VI secretion system translocates a phage tail spike-like protein into target cells where it cross-links actin.
Genes encoding type VI secretion systems (T6SS) are widely distributed in pathogenic Gram-negative bacterial species. In Vibrio… (More)
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Review
2007
Review
2007
Coronavirus avian infectious bronchitis virus.
Infectious bronchitis virus (IBV), the coronavirus of the chicken (Gallus gallus), is one of the foremost causes of economic loss… (More)
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Highly Cited
2005
Highly Cited
2005
Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma.
Bortezomib, as a single agent and in combination with dexamethasone, was examined as first-line treatment in 32 consecutive… (More)
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Highly Cited
2004
Highly Cited
2004
Identification of a new human coronavirus
Three human coronaviruses are known to exist: human coronavirus 229E (HCoV-229E), HCoV-OC43 and severe acute respiratory syndrome… (More)
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Highly Cited
2003
Highly Cited
2003
The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex.
Coronavirus entry is mediated by the viral spike (S) glycoprotein. The 180-kDa oligomeric S protein of the murine coronavirus… (More)
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Highly Cited
2003
Highly Cited
2003
Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival.
Multiple myeloma is characterized by the growth of plasma cells in the bone marrow and the development of osteolytic bone disease… (More)
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Highly Cited
2002
Highly Cited
2002
Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma.
Thalidomide (Thal) can overcome drug resistance in multiple myeloma (MM) but is associated with somnolence, constipation, and… (More)
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Highly Cited
1999
Highly Cited
1999
Antitumor activity of thalidomide in refractory multiple myeloma.
BACKGROUND Patients with myeloma who relapse after high-dose chemotherapy have few therapeutic options. Since increased bone… (More)
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