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Lymphocyte Culture Test, Mixed

Known as: Mixed Lymphocyte Culture Test, Mixed Leukocyte Culture Test, Leukocyte Reaction, Mixed 
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several… 
National Institutes of Health

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Broader (1)

Histocompatibility Testing

Papers overview

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Highly Cited
1999
Highly Cited
1999
Human lung dendritic cells have an immature phenotype with efficient mannose receptors.
Dendritic cells (DC) can be present at distinct stages of differentiation within the immune system. Sallusto and colleagues have… 
Highly Cited
1993
Highly Cited
1993
Specific interaction of lymphocyte function-associated antigen 3 with CD2 can inhibit T cell responses
Accessory cell surface molecules, such as T cell antigen CD2 and its ligand lymphocyte function-associated antigen 3 (LFA-3; CD58… 
Highly Cited
1984
Highly Cited
1984
Acquisition of specific cytotoxic activity by human T4+ T lymphocytes in culture
Mature human T lymphocytes can be separated by monoclonal antibodies OKT4 and OKT8 according to their surface phenotypes into T4… 
Highly Cited
1981
Highly Cited
1981
Activation of human T lymphocyte subsets: helper and suppressor/cytotoxic T cells recognize and respond to distinct histocompatibility antigens.
This study was directed at determining the major histocompatibility complex (MHC) antigens recognized by helper (Leu-3) and… 
Highly Cited
1981
Highly Cited
1981
Regulation of macrophage populations. II. Synthesis and expression of Ia antigens by peritoneal exudate macrophages is a transient event.
We have evaluated the biosynthesis and surface expression of I-A antigens by peritoneal macrophages and found that both events… 
Highly Cited
1980
Highly Cited
1980
Macrophage heterogeneity in man. A subpopulation of HLA-DR-bearing macrophages required for antigen-induced T cell activation also contains stimulators for autologous-reactive T cells
Utilizing somatic cell hybridization, we have developed a monoclonal antibody that interacts only with cells of the monocyte… 
Highly Cited
1980
Highly Cited
1980
Characterization of a human macrophage-like cell line stimulated in vitro: a model of macrophage functions.
When cells of human macrophage-like cell line U937 are cultured in the presence of medium conditioned by mixed lymphocyte culture… 
Highly Cited
1977
Highly Cited
1977
Antigen presentation in the murine T-lymphocyte proliferative response. I. Requirement for genetic identity at the major histocompatibility complex
A method is described for stimulating proliferation in primed populations of murine T lymphocytes using antigen bound to… 
Highly Cited
1975
Highly Cited
1975
HL-A LD (lymphocyte defined) typing: a rapid assay with primed lymphocytes.
When human lymphocytes are cultured for 9 to 14 days with stimulating cells of a family member differing by a single HL-A… 
Highly Cited
1973
Highly Cited
1973
CELL-MEDIATED LYMPHOLYSIS
The cell-mediated lympholytic capability of mouse spleen cells stimulated in mixed lymphocyte culture is related to the major… 
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