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Lofexidine hydrochloride

Known as: 2-(1-(2,6-Dichlorophenoxy)Ethyl)-2-Imidazoline Monohydrochloride, 1H-Imidazole, 2-(1-(2,6-Dichlorophenoxy)Ethyl)-4,5-Dihydro-, Monohydrochloride, Lofexidine mono-hydrochloride 
National Institutes of Health

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Papers overview

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Review
2019
Review
2019
Clinical Efficacy and Safety Profile of Lofexidine Hydrochloride in Treating Opioid Withdrawal Symptoms: A Review of Literature
Opioid use disorder (OUD) is a rapidly growing challenge worldwide and is characterized by an increase in dependence on opioids… 
2019
2019
Differences in the Receptor Binding Profile of Lofexidine Compared to Clonidine
Lucemyra® (lofexidine hydrochloride) has recently been approved by the US FDA for the mitigation of withdrawal symptoms to… 
Review
2018
Review
2018
Drug updates and approvals: 2018 in review.
In 2018, the FDA approved several new drugs for use in primary care. This article highlights the following new drugs: bictegravir… 
2016
2016
Psychometric evaluation of the 10-item Short Opiate Withdrawal Scale-Gossop (SOWS-Gossop) in patients undergoing opioid detoxification.
2016
2016
Pharmaceutical Approval Update.
Defibrotide sodium (Defitelio) for hepatic veno-occlusive disease; emtricitabine/tenofovir alafenamide (Descovy) for human… 
2009
2009
Pharmacokinetics of lofexidine hydrochloride in healthy volunteers.
The objective of this study was to characterize the clinical pharmacokinetic profile of lofexidine after oral delivery. A single… 
2005
2005
[Clinical application of acupuncture for treatment of heroin withdrawal syndrome].
OBJECTIVE To make technical standard of acupuncture manipulation for acupuncture treatment of heroin withdrawal syndrome… 
2001
2001
Randomized placebo controlled trial of lofexidine hydrochloride for chronic pelvic pain in women.
BACKGROUND We hypothesised that the orally-active alpha(2)-adrenoceptor agonist lofexidine hydrochloride would ameliorate chronic… 
1999
1999
Audit of the in-patient management of opioid withdrawal using lofexidine hydrochloride
Over a period of 24 months, data were collected on 214 opioid detoxifications (190 patients), based on lofexidine hydrochloride… 
Review
1990
Review
1990
Pharmacologic Interventions for the Treatment of Opioid Dependence and Withdrawal
  • S. Guthrie
  • DICP : the annals of pharmacotherapy
  • 1990
  • Corpus ID: 23355474
This article discusses current pharmacologic methods in the treatment of heroin dependence and withdrawal. Methadone… 
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