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Liter Per Hour Per Square Meter
Known as:
(l/h)/m2
, L/h/m2
, Liters per Hour per Square Meter
A unit expressed as one liter of volume per unit of time equal to one hour per square meter of area.
National Institutes of Health
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Clinical Data Interchange Standards Consortium Terminology
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Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Pharmacokinetics of TH-302: a hypoxically activated prodrug of bromo-isophosphoramide mustard in mice, rats, dogs and monkeys
D. Jung
,
Lin Lin
,
H. Jiao
,
Xiaohong Cai
,
Jianxin Duan
,
M. Matteucci
Cancer Chemotherapy and Pharmacology
2012
Corpus ID: 22506044
PurposeTo characterize the pharmacokinetics of the prodrug, TH-302, and its active metabolite, bromo-IPM (Br-IPM), in nonclinical…
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2007
2007
F-ara-A pharmacokinetics during reduced-intensity conditioning therapy with fludarabine and busulfan
M. Bonin
,
S. Pursche
,
+5 authors
M. Bornhäuser
Bone Marrow Transplantation
2007
Corpus ID: 10389881
Fludarabine is commonly used in combination with busulfan as part of conditioning regimens before allogeneic stem cell…
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Highly Cited
2005
Highly Cited
2005
Lack of effect of aprepitant on the pharmacokinetics of docetaxel in cancer patients
P. Nygren
,
K. Hande
,
+10 authors
S. Van Belle
Cancer Chemotherapy and Pharmacology
2005
Corpus ID: 29709720
BackgroundAprepitant is a selective neurokinin-1 receptor antagonist that is effective for the prevention of nausea and vomiting…
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Highly Cited
2001
Highly Cited
2001
Relationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patients.
A. Paolo
,
R. Danesi
,
+8 authors
M. Tacca
Annals of Oncology
2001
Corpus ID: 34297481
BACKGROUND Previous work demonstrated that 5-fluorouracil (5-FU) metabolism is a critical factor for treatment tolerability. In…
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2001
2001
Phase I dose-finding and pharmacokinetic trial of irinotecan (CPT-11) administered every two weeks.
M. Rothenberg
,
J. Kuhn
,
+12 authors
D. V. Hoff
Annals of Oncology
2001
Corpus ID: 42510728
OBJECTIVES This trial was performed to determine the maximum tolerated dose (MTD), dose-limiting toxicity (DLT), and…
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2000
2000
Population Pharmacokinetics/Toxicodynamics (PK/TD) Relationship of SAM486A in Phase I Studies in Patients with Advanced Cancers
Honghui Zhou
,
L. Choi
,
+9 authors
R. Capdeville
Journal of clinical pharmacology
2000
Corpus ID: 23998433
SAM486A (previously termed CGP 48664), a potent inhibitor of S‐adenosylmethionine decarboxylase, is under clinical development…
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2000
2000
A phase I clinical and pharmacokinetic study of the dolastatin analogue cemadotin administered as a 5-day continuous intravenous infusion
J. Supko
,
T. Lynch
,
+5 authors
Joseph Paul Eder Jr
Cancer Chemotherapy and Pharmacology
2000
Corpus ID: 26146101
Purpose: The dolastatins are a class of naturally occurring cytotoxic peptides which function by inhibiting microtubule assembly…
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1999
1999
The effect of fluconazole on cyclophosphamide metabolism in children.
S. Yule
,
D. Walker
,
+5 authors
Alan V. Boddy
Drug Metabolism And Disposition
1999
Corpus ID: 14367557
Fluconazole is increasingly used in children receiving chemotherapy. Many of these patients are being treated with…
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Highly Cited
1992
Highly Cited
1992
A phase I clinical and pharmacokinetic study of the topoisomerase I inhibitor topotecan (SK&F 104864) given as an intravenous bolus every 21 days
J. Wall
,
H. Burris
,
+13 authors
J. Kuhn
Anti-Cancer Drugs
1992
Corpus ID: 24090622
Topotecan (SK&F 104864) is a novel antitumor agent whose mechanism of action is inhibition of the DNA unwinding protein…
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1988
1988
Pharmacokinetics and metabolism of pirarubicin in advanced cancer patients.
J. Robert
,
M. David
,
S. Huet
,
J. Chauvergne
European Journal of Cancer and Clinical Oncology
1988
Corpus ID: 26116782
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