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Linear Amplification Technique

Various methods for amplification of nucleic acid sequences by making many copies off the same template.
National Institutes of Health

Papers overview

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2018
2018
Single-cell RNA Sequencing of Fluorescently Labeled Mouse Neurons Using Manual Sorting and Double In Vitro Transcription with Absolute Counts Sequencing (DIVA-Seq).
Single-cell RNA sequencing (RNA-seq) is now a widely implemented tool for assaying gene expression. Commercially available single… 
2010
2010
articleDownregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFδ / δ mouse model of amyotrophic lateral sclerosis
Background: Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that stimulates vasculogenesis. It has also… 
2006
2006
An evaluation of linear RNA amplification in cDNA microarray gene expression analysis.
2004
2004
Evaluation of a linear amplification method for small samples used on high-density oligonucleotide microarray analysis.
1997
1997
Interaction of 11 cisplatin analogues with DNA: characteristic pattern of damage with monofunctional analogues.
1995
1995
Comparison of the sequence selectivity of the DNA-alkylating pluramycin antitumour antibiotics DC92-B and hedamycin.
1993
1993
Direct sequencing of lambda DNA from crude lysates using an improved linear amplification technique.
We describe an improved method for directly sequencing lambda (lambda) DNA that has been isolated from either crude cleared… 
Highly Cited
1992
Highly Cited
1992
An investigation of the sequence-specific interaction of cis-diamminedichloroplatinum(II) and four analogues, including two acridine-tethered complexes, with DNA inside human cells.
The sequence specificity of DNA damage caused by cis-diamminedichloroplatinum(II) (cisplatin) and four analogues in human (HeLa… 
1991
1991
Sequenase should be used instead of the Klenow fragment for the synthesis of oligonucleotides labeled to a high specific activity.
When using oligonucleotides as probes in Southern hybridization with genomes of high complexity it is important to use very hot… 
1990
1990
Low pressure DNA shearing: a method for random DNA sequence analysis.
Several methods have been described for random fragmentation of DNA. These methods, often used for library preparation and… 
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