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Liddle Syndrome

Known as: Pseudoaldosteronism, LIDLS, PSEUDOHYPERALDOSTERONISM 
Familial pseudoaldosteronism characterized by autosomal dominant inheritance of hypertension with HYPOKALEMIA; ALKALOSIS; RENIN and ALDOSTERONE level… 
National Institutes of Health

Related topics

Related topics

10 relations
Bartter DiseaseIn BloodMicrobiologicalSCNN1B gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Truncated beta epithelial sodium channel (ENaC) subunits responsible for multi-system pseudohypoaldosteronism support partial activity of ENaC
Review
2005
Review
2005
Channels, carriers, and pumps in the pathogenesis of sodium-sensitive hypertension.
2005
2005
A novel epithelial sodium channel β-subunit mutation associated with hypertensive Liddle syndrome
Low-renin hypertension responsive to amiloride-thiazide therapy in a 4-year-old Afro-Haitian girl suggested Liddle syndrome… 
2002
2002
Glycyrrhizic acid suppresses type 2 11β-hydroxysteroid dehydrogenase expression in vivo
Review
2000
Review
2000
Disorders of the Epithelial Na+ Channel in Liddle’s Syndrome and Autosomal Recessive Pseudohypoaldosteronism Type 1
The epithelial Na+ channel (ENaC) is the key step in many Na+-absorptive epithelia, such as kidney and distal colon, that… 
1999
1999
Effect of subunit composition and Liddle's syndrome mutations on biosynthesis of ENaC.
The epithelial Na+ channel (ENaC) is comprised of three homologous subunits: alpha, beta, and gamma, all of which are required… 
1999
1999
Cystic Fibrosis Transmembrane Conductance Regulator Inhibits Epithelial Na+ Channels Carrying Liddle’s Syndrome Mutations*
Epithelial Na+ channels (ENaC) are inhibited by the cystic fibrosis transmembrane conductance regulator (CFTR) upon activation by… 
Highly Cited
1999
Highly Cited
1999
Genetic variants in the epithelial sodium channel in relation to aldosterone and potassium excretion and risk for hypertension.
Renin and aldosterone secretion is often lower in blacks than in whites, characteristics that resemble a milder form of Liddle… 
Highly Cited
1999
Highly Cited
1999
Quantitative trait loci for blood pressure exist near the IGF-1, the Liddle syndrome, the angiotensin II-receptor gene and the renin loci in man.
Blood pressure (BP) is heritable and finding quantitative trait loci that influence BP is an important step in identifying genes… 
1998
1998
The diagnosis of Liddle syndrome by identification of a mutation in the beta subunit of the epithelial sodium channel.
Hypertension is a common multifactorial disorder associated with considerable morbidity and mortality. The kidney plays a major… 
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