Leuprolide

Known as: Leuprorelinum, PGlu-his-trp-ser-tyr-D-leu-leu-arg-pro-NHC2H5, (D-Leu(6),des-gly-NH2(10),pro-ethylamide(9))-gonadotropin-releasing hormone 
A synthetic nonapeptide analogue of gonadotropin-releasing hormone. Leuprolide binds to and activates gonadotropin-releasing hormone (GnRH) receptors… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
05010019542016

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND The efficacy and side-effect profile of ulipristal acetate as compared with those of leuprolide acetate for the… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Dienogest is a selective progestin that has been investigated in a clinical trial programme for the treatment of… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE To evaluate the efficacy and safety of degarelix, a new gonadotrophin-releasing hormone (GnRH) antagonist (blocker), vs… (More)
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Highly Cited
2003
Highly Cited
2003
Spinal and bulbar muscular atrophy (SBMA) is an adult-onset motor neuron disease that affects males. It is caused by the… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Treatment with a gonadotropin-releasing hormone agonist decreases bone mineral density and increases the risk of… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Combined androgen blockade for the treatment of metastatic prostate cancer consists of an antiandrogen drug plus… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The symptoms of women with premenstrual syndrome improve in response to suppression of ovarian function, although… (More)
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Highly Cited
1991
Highly Cited
1991
The relationship of the circulating level of progesterone (P) on the day of human chorionic gonadotropin (hCG) injection to… (More)
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Highly Cited
1989
Highly Cited
1989
To test the hypothesis that maximal androgen blockade improves the effectiveness of the treatment of prostatic cancer, we… (More)
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Highly Cited
1984
Highly Cited
1984
  • The New England journal of medicine
  • 1984
We compared the efficacy and safety of the gonadotropin-releasing hormone analogue, leuprolide (1 mg subcutaneously daily), with… (More)
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