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Leuprolide

Known as: Leuprorelinum, PGlu-his-trp-ser-tyr-D-leu-leu-arg-pro-NHC2H5, (D-Leu(6),des-gly-NH2(10),pro-ethylamide(9))-gonadotropin-releasing hormone 
A synthetic nonapeptide analogue of gonadotropin-releasing hormone. Leuprolide binds to and activates gonadotropin-releasing hormone (GnRH) receptors… 
National Institutes of Health

Related topics

Related topics

46 relations
1 ML Leuprolide Acetate 11.25 MG/ML Prefilled Syringe [Lupron]1 ML Leuprolide Acetate 15 MG/ML Prefilled Syringe [Lupron]1 ML Leuprolide Acetate 7.5 MG/ML Prefilled Syringe [Lupron]1.5 ML Leuprolide Acetate 20 MG/ML Prefilled Syringe [Lupron]

Narrower (15)

A-43818EligardEnantoneEnantone-Gyn

Broader (3)

Antineoplastic AgentsAntineoplastic Agents, HormonalFertility Agents, Female

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
Effect of turosteride, a 5α‐reductase inhibitor, on the Dunning R3327 rat prostatic carcinoma
Turosteride (FCE 26073) is a new, potent, and selective 5α‐reductase inhibitor. We have investigated its effect on tumor growth… 
1996
1996
Treatment and prophylaxis of hypermenorrhea with leuprorelin in premenopausal women affected by acute leukemia at diagnosis
1991
1991
Effects of LHRH-analogue treatment of spermatogenic dysfunction in the dog.
Three male dogs, aged 2-4 years, which exhibited a high percentage of sperm with abnormal tails in their semen and low levels of… 
1984
1984
Vaginal absorption of a potent luteinizing hormone-releasing hormone analogue (leuprolide) in rats. IV: Evaluation of the vaginal absorption and gonadotropin responses by radioimmunoassay.
The vaginal absorption of leuprolide (a potent luteinizing hormone-releasing hormone analogue), which has the potential for… 
1984
1984
Effect of an LHRH agonist on pituitary and testicular function in rhesus monkeys.
Male rhesus monkeys were given 100 micrograms [(imBzl)-D-His6,Pro9-NEt]-LHRH (LHRH-A), a potent LHRH agonist, s.c. daily for 40… 
1984
1984
Leuprolide therapy for prostatic carcinoma
Seventy thousand new cases of prostate carcinoma are diagnosed in the United States yearly (Silverberg and Holleb, 1982). At… 
Highly Cited
1983
Highly Cited
1983
Vaginal absorption of a potent luteinizing hormone-releasing hormone analogue (leuprolide) in rats II: mechanism of absorption enhancement with organic acids.
Organic acids such as citric acid enhance the vaginal absorption of luteinizing hormone-releasing hormone, the potent analogue… 
1983
1983
Specific, estrogen-sensitive alterations in anterior pituitary cytoplasmic and nuclear estrogen receptors actuated by LHRH.
We have previously demonstrated that LHRH is capable of eliciting a dramatic and direct elevation of anterior pituitary levels of… 
1983
1983
Regression of rat mammary tumors by a potent luteinizing hormone-releasing hormone analogue (leuprolide) administered vaginally.
Potent luteinizing hormone-releasing hormone analogues are known to cause regression of hormone-dependent mammary tumors. We have… 
1983
1983
Desensitization of gonadotropin-releasing response following vaginal consecutive administration of leuprolide in rats.
The vaginal absorption of a potent luteinizing hormone-releasing hormone analog (leuprolide), and the gonadotropins (luteinizing…