Let-7

Known as: hsa-let-7, MIRLET7, Let-7 miRNA 
A microRNA that has seven isofoms and is known to be a regulator of the RAS oncogene. The length of the miRNA is ~22 nucleotides, and the 3' UTR is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2017
02040608020052017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Diabetes mellitus is the most common metabolic disorder worldwide and a major risk factor for cardiovascular disease. MicroRNAs… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Exosomes play a major role in cell-to-cell communication, targeting cells to transfer exosomal molecules including… (More)
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Highly Cited
2010
Highly Cited
2010
In recent years, various RNA-based technologies have been under evaluation as potential next-generation cancer therapeutics… (More)
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Highly Cited
2009
Highly Cited
2009
Inflammation is linked clinically and epidemiologically to cancer, and NF-kappaB appears to play a causative role, but the… (More)
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Highly Cited
2008
Highly Cited
2008
A hallmark of mammalian embryonic development is the widespread induction of microRNA (miRNA) expression. Surprisingly, the… (More)
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Highly Cited
2008
Highly Cited
2008
MicroRNAs (miRNA) are small RNA molecules of approximately 20 to 22 nucleotides that reduce expression of proteins through mRNA… (More)
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Highly Cited
2007
Highly Cited
2007
MicroRNAs (miRNAs) are approximately 22-nucleotide RNAs that can pair to sites within messenger RNAs to specify… (More)
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Highly Cited
2007
Highly Cited
2007
The early phases of carcinogenesis resemble embryonic development, often involving the reexpression of embryonic mesenchymal… (More)
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Highly Cited
2007
Highly Cited
2007
MicroRNAs (miRNAs) are incorporated into miRNP complexes and regulate protein expression post-transcriptionally through binding… (More)
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Highly Cited
2005
Highly Cited
2005
MicroRNAs (miRNAs) are approximately 21-nucleotide-long RNA molecules regulating gene expression in multicellular eukaryotes. In… (More)
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