Lamin Type A

Known as: Lamin Type A [Chemical/Ingredient], Type A Lamins, Lamin A C 
A subclass of developmentally regulated lamins having a neutral isoelectric point. They are found to disassociate from nuclear membranes during… (More)
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Tissues can be soft like fat, which bears little stress, or stiff like bone, which sustains high stress, but whether there is a… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in the nuclear structural protein lamin A cause the premature aging syndrome Hutchinson-Gilford progeria (HGPS… (More)
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Highly Cited
2004
Highly Cited
2004
Mutations in the lamin A/C gene (LMNA) cause a variety of human diseases including Emery-Dreifuss muscular dystrophy, dilated… (More)
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Highly Cited
2004
Highly Cited
2004
Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disorder, commonly caused by a point mutation in the lamin A… (More)
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Highly Cited
2003
Highly Cited
2003
Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by features reminiscent of marked premature… (More)
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Highly Cited
2000
Highly Cited
2000
A BSTRACT Background Inherited mutations cause approximately 35 percent of cases of dilated cardiomyopathy; however, few genes… (More)
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Highly Cited
2000
Highly Cited
2000
The lipodystrophies are a group of disorders characterized by the absence or reduction of subcutaneous adipose tissue. Partial… (More)
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Highly Cited
1996
Highly Cited
1996
Expression of the adenovirus E1A oncogene stimulates both cell proliferation and p53-dependent apoptosis in rodent cells. p53… (More)
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Highly Cited
1993
Highly Cited
1993
We have determined the structural organization of the human gene that encodes nuclear lamins A and C, intermediate filament… (More)
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Highly Cited
1986
Highly Cited
1986
The amino acid sequences deduced from cDNA clones of human lamin A and lamin C show identity between these two lamins except for… (More)
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