LMNA gene

Known as: LAMIN C, HGPS, PROGERIN 
This gene is involved in the architecture of nuclear membrane construction.
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disorder, commonly caused by a point mutation in the lamin A… (More)
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Highly Cited
2004
Highly Cited
2004
H utchinson-Gilford Progeria Syndrome (HGPS, OMIM 176670), commonly called ‘‘progeria’’, occurs in <1 in 8 million births and… (More)
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Highly Cited
2003
Highly Cited
2003
Small interfering RNAs (siRNAs) induce sequence-specific gene silencing in mammalian cells and guide mRNA degradation in the… (More)
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Highly Cited
2003
Highly Cited
2003
AbstractHutchinson-Gilford progeria syndrome (HGPS; MIM 176670) is an extremely rare disease that is characterized by accelerated… (More)
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Highly Cited
2002
Highly Cited
2002
Mandibuloacral dysplasia (MAD) is a rare autosomal recessive disorder, characterized by postnatal growth retardation… (More)
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Highly Cited
2002
Highly Cited
2002
The Charcot-Marie-Tooth (CMT) disorders comprise a group of clinically and genetically heterogeneous hereditary motor and sensory… (More)
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Highly Cited
2001
Highly Cited
2001
We report the first RNAi-induced phenotypes in mammalian cultured cells using RNA interference mediated by duplexes of 21-nt RNAs… (More)
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Highly Cited
2000
Highly Cited
2000
The lipodystrophies are a group of disorders characterized by the absence or reduction of subcutaneous adipose tissue. Partial… (More)
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Highly Cited
1996
Highly Cited
1996
Phylogenetic analysis of the CED-3/ICE family of cysteine proteases suggests the existence of a subfamily most related to the… (More)
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Highly Cited
1993
Highly Cited
1993
We have determined the structural organization of the human gene that encodes nuclear lamins A and C, intermediate filament… (More)
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