LYPD6 gene

Known as: LYPD6, LY6/PLAUR domain containing 6, MGC52057 
 
National Institutes of Health

Papers overview

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2018
2018
Structure of the Wnt signaling enhancer LYPD6 and its interactions with the Wnt coreceptor LRP6.
Ly6/urokinase-type plasminogen activator receptor (uPAR) (LU) domain containing 6 (LYPD6) is a Wnt signaling enhancer that… Expand
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2017
2017
Whole-Genome Sequencing of Cytogenetically Balanced Chromosome Translocations Identifies Potentially Pathological Gene Disruptions and Highlights the Importance of Microhomology in the Mechanism of…
Most balanced translocations are thought to result mechanistically from nonhomologous end joining or, in rare cases of recurrent… Expand
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2017
2017
Recombinant production and structural studies of the human Lypd6 and Lypd6b proteins
Lypd6 and Lypd6b are human three-finger proteins expressed in various tissues and sharing a high degree of sequence homology (~54… Expand
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2017
2017
Loss of Lypd6 leads to reduced anxiety-like behaviour and enhanced responses to nicotine
Nicotine consumption through smoking affects anxious states in humans. However, the precise role of nicotinic acetylcholine… Expand
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2016
2016
Bacterial expression system and structural-functional studies of human Lypd6
 
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2015
2015
Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disorder involving impaired cholinergic neurotransmission and dysregulation of… Expand
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2014
2014
Cortical parvalbumin and somatostatin GABA neurons express distinct endogenous modulators of nicotinic acetylcholine receptors
BackgroundInhibition from GABAergic interneurons in brain circuits is a critical component of cognitive function. This inhibition… Expand
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2009
2009
Modulation of the Ca2+ conductance of nicotinic acetylcholine receptors by Lypd6
The agonist binding sensitivity and desensitization kinetics of nicotinic acetylcholine receptors (nAChRs) can be modulated by… Expand
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2009
2009
Identification and characterization of human LYPD6, a new member of the Ly-6 superfamily
The Ly-6 protein superfamily is usually identified as a group of proteins with a LU protein domain. LU domain is about 80 amino… Expand
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2009
2009
Modulation of the Ca 2 + Conductance of Nicotinic Acetylcholine Receptors by Lypd 6
The agonist binding sensitivity and desensitization kinetics of nicotinic acetylcholine receptors (nAChRs) can be modulated by… Expand
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