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LYPD6 gene

Known as: LYPD6, LY6/PLAUR domain containing 6, MGC52057 
 
National Institutes of Health

Papers overview

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2020
2020
Activation of Somatostatin Interneurons by Nicotinic Modulator Lypd6 Enhances Plasticity and Functional Recovery in the Adult Mouse Visual Cortex
The limitation of plasticity in the adult brain impedes functional recovery later in life from brain injury or disease. This… Expand
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2018
2018
Structure of the Wnt signaling enhancer LYPD6 and its interactions with the Wnt coreceptor LRP6
Ly6/urokinase‐type plasminogen activator receptor (uPAR) (LU) domain containing 6 (LYPD6) is a Wnt signaling enhancer that… Expand
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2018
2018
Loss of Lypd6 leads to reduced anxiety-like behaviour and enhanced responses to nicotine
&NA; Nicotine consumption through smoking affects anxious states in humans. However, the precise role of nicotinic acetylcholine… Expand
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2018
2018
Global epigenetic analysis of BDNF Val66Met mice hippocampus reveals changes in dendrite and spine remodeling genes
Brain‐derived neurotrophic factor (BDNF), a neurotrophin highly expressed in the hippocampus, plays crucial roles in cognition… Expand
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2017
2017
Whole‐Genome Sequencing of Cytogenetically Balanced Chromosome Translocations Identifies Potentially Pathological Gene Disruptions and Highlights the Importance of Microhomology in the Mechanism of…
Most balanced translocations are thought to result mechanistically from nonhomologous end joining or, in rare cases of recurrent… Expand
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2015
2015
Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disorder involving impaired cholinergic neurotransmission and dysregulation of… Expand
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2014
2014
Cortical parvalbumin and somatostatin GABA neurons express distinct endogenous modulators of nicotinic acetylcholine receptors
BackgroundInhibition from GABAergic interneurons in brain circuits is a critical component of cognitive function. This inhibition… Expand
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2009
2009
Modulation of the Ca2+ conductance of nicotinic acetylcholine receptors by Lypd6
The agonist binding sensitivity and desensitization kinetics of nicotinic acetylcholine receptors (nAChRs) can be modulated by… Expand
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2009
2009
Identification and characterization of human LYPD6, a new member of the Ly-6 superfamily
The Ly-6 protein superfamily is usually identified as a group of proteins with a LU protein domain. LU domain is about 80 amino… Expand
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2009
2009
Modulation of the Ca 2 + Conductance of Nicotinic Acetylcholine Receptors by Lypd 6
The agonist binding sensitivity and desensitization kinetics of nicotinic acetylcholine receptors (nAChRs) can be modulated by… Expand
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