• Publications
  • Influence
Modulation of excitatory synaptic transmission by nociceptin in superficial dorsal horn neurones of the neonatal rat spinal cord
The modulatory actions of nociceptin/orphanin FQ on excitatory synaptic transmission were studied in superficial dorsal horn neurones in transverse slices from 7 to 14 day old rats. GlutamatergicExpand
  • 120
  • 13
  • PDF
Calcium-activated non-selective channels in the nervous system
In the decade, since the first description of calcium-activated non-selective (CAN) channels in cardiac myocytes, pancreatic acini and neuroblastoma, this type of channel has been shown to have aExpand
  • 102
  • 12
Calcium-activated non-specific cation channels
Abstract Calcium-activated non-specific cation (CAN) channels are found in a broad range of cells, including cardiac cells, secretory cells, and neurons. Single channel recordings indicate that theseExpand
  • 278
  • 11
Glial cells are born with synapses
In postnatal rodent brain, certain NG2‐expressing oligodendroglial precursor cells (OPCs) are contacted by synaptic terminals from local neurons. However, it has remained elusive whether and whenExpand
  • 102
  • 10
Role of residual calcium in synaptic depression and posttetanic potentiation: Fast and slow calcium signaling in nerve terminals
Trains of action potentials evoked rises in presynaptic Ca2+ concentration ([Ca2+]i) at the squid giant synapse. These increases in [Ca2+]i were spatially nonuniform during the trains, but rapidlyExpand
  • 181
  • 9
Fast-deactivating calcium channels in chick sensory neurons
Whole-cell Ca and Ba currents were studied in chick dorsal root ganglion (DRG) cells kept 6-10 in culture. Voltage steps with a 15- microseconds rise time were imposed on the membrane using anExpand
  • 140
  • 7
  • PDF
Menthol Suppresses Nicotinic Acetylcholine Receptor Functioning in Sensory Neurons via Allosteric Modulation
In this study, we have investigated how the function of native and recombinant nicotinic acetylcholine receptors (nAChRs) is modulated by the monoterpenoid alcohol from peppermint (−) menthol. InExpand
  • 64
  • 7
  • PDF
A diacylglycerol analogue reduces neuronal calcium currents independently of protein kinase C activation
DIACYLGLYCEROL analogues (for example 1,2-oleoylacetyl-glycerol, OAG) and phorbol esters are activators of protein kinase C, and have been widely used to study the function of this enzyme in bothExpand
  • 168
  • 6
Differential effects of ketamine enantiomers on NMDA receptor currents in cultured neurons.
The effects of R- and S-ketamine on N-methyl-D-aspartate receptor-activated cation currents (NMDA receptor currents) of voltage-clamped cultured rat hippocampal neurons were investigated using theExpand
  • 115
  • 6
Neuronal calcium channels: kinetics, blockade and modulation.
  • 182
  • 5