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LYL1 gene

Known as: LYMPHOBLASTIC LEUKEMIA-DERIVED SEQUENCE 1, LYL1, bHLHa18 
This gene plays a role in transcriptional regulation and is involved in the pathogenesis of acute lymphoblastic leukemia.
National Institutes of Health

Related topics

Related topics

4 relations
Acute lymphocytic leukemiaLYL1 protein, humanLigand Bindingdna binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The NUP98-HOXD13 fusion oncogene induces thymocyte self-renewal via Lmo2/Lyl1
T cell acute lymphoblastic leukaemia (T-ALL) cases include subfamilies that overexpress the TAL1/LMO, TLX1/3 and HOXA… 
2015
2015
Characterisation of a compound in-cis GATA2 germline mutation in a pedigree presenting with myelodysplastic syndrome/acute myeloid leukemia with concurrent thrombocytopenia
Characterisation of a compound in - cis GATA2 germline mutation in a pedigree presenting with myelodysplastic syndrome/acute… 
2015
2015
Enforced expression of E47 has differential effects on Lmo2-induced T-cell leukemias.
2012
2012
Suspected leukemia oncoproteins CREB1 and LYL1 regulate Op18/STMN1 expression.
2009
2009
JAK1 mutation analysis in T-cell acute lymphoblastic leukemia cell lines
T-cell acute lymphoblastic leukemia (T-ALL) is a malignancy of T-cell precursors that mainly occurs in children and adolescents… 
2009
2009
It's not palliative care, it's palliative treatment.
2000
2000
A novel translocation (17;19)(p13;p13) in a patient with acute myelomonocytic leukemia.
Highly Cited
1996
Highly Cited
1996
Association of a novel GTP binding protein, DRG, with TAL oncogenic proteins.
TAL1 is a basic helix-loop-helix (bHLH) protein involved in hematopoietic development. In T cell acute lymphoblastic leukemic… 
1994
1994
Products of the TAL2 oncogene in leukemic T cells: bHLH phosphoproteins with DNA-binding activity.
The TAL2 gene is activated as a result of the (7;9) (q34;q32) translocation, a chromosome defect found in the malignant cells of… 
1991
1991
Structure, chromosome mapping, and expression of the mouse Lyl-1 gene.
The mouse Lyl-1 gene was cloned and shown to consist of four exons with extensive nucleotide and structural homology to the human… 
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