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LYL1 gene
Known as:
LYMPHOBLASTIC LEUKEMIA-DERIVED SEQUENCE 1
, LYL1
, bHLHa18
Â
(More)
This gene plays a role in transcriptional regulation and is involved in the pathogenesis of acute lymphoblastic leukemia.
National Institutes of Health
Topic mentions per year
Topic mentions per year
1991-2017
0
2
4
1991
2017
Related topics
Related topics
4 relations
Acute lymphocytic leukemia
LYL1 protein, human
Ligand Binding
dna binding
Related mentions per year
Related mentions per year
1946-2018
1940
1960
1980
2000
2020
LYL1 gene
dna binding
Acute lymphocytic leukemia
Ligand Binding
LYL1 protein, human
Papers overview
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2014
2014
Lung endothelial barrier disruption in Lyl1-deficient mice.
Nelly Pirot
,
Hélène Delpech
,
+6 authors
Valérie Pinet
American journal of physiology. Lung cellular and…
2014
Maturation of newly formed vessels is a multistep phenomenon during which functional endothelial barriers are established…Â
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2012
2012
Characterization of a pediatric T-cell acute lymphoblastic leukemia patient with simultaneous LYL1 and LMO2 rearrangements.
Irene Homminga
,
Maartje J. Vuerhard
,
Anton W. Langerak
,
Jessica G C A M Buijs-Gladdines
,
Rob Pieters
,
Jules P P Meijerink
Haematologica
2012
Translocation of the LYL1 oncogene are rare in T-cell acute lymphoblastic leukemia, whereas the homologous TAL1 gene is…Â
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2012
2012
Suspected leukemia oncoproteins CREB1 and LYL1 regulate Op18/STMN1 expression.
Serban San-Marina
,
Youqi Han
,
Jian Liu
,
Mark D Minden
Biochimica et biophysica acta
2012
Stathmin (STMN1) is a microtubule destabilizing protein with a key role in cell cycle progression and cell migration that is up…Â
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2009
2009
[Abnormal expression of transcription factors LYL1 and LMO2 and interaction between them in myeloid leukemia].
Yue-sheng Meng
,
Rong Wei
,
Gong-wen Ai
,
Xiu-qin Meng
,
Yan-xiang Zhang
Zhonghua yi xue za zhi
2009
OBJECTIVE To explore the expression of the transcription factors LMO2 and LYL1 and the interaction between these 2 factors in…Â
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2008
2008
[Expression of transcription factor LYL1 in leukemia and its possible role in leukemogenesis].
Yue-sheng Meng
,
Yan-xiang Zhang
,
+4 authors
Wei Jiang
Zhonghua xue ye xue za zhi = Zhonghua xueyexue…
2008
OBJECTIVE To study the expression of transcription factor LYL1 in leukemia and its possible role in leukemogenesis. METHODS…Â
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2005
2005
Oncogenic potential of the transcription factor LYL1 in acute myeloblastic leukemia
Y-S Meng
,
H. Jean Khoury
,
Justin Dick
,
Mark D Minden
Leukemia
2005
The LYL1 gene encodes a basic helix–loop–helix transcription factor involved in T-cell acute lymphoblastic leukemia. Using real…Â
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2004
2004
Age-related phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy.
Vahid Asnafi
,
Kheira Beldjord
,
+8 authors
Elizabeth T Macintyre
Blood
2004
Postnatal thymic involution occurs progressively throughout the first 3 decades of life. It predominantly affects T-cell receptor…Â
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2003
2003
Comparative and functional analyses of LYL1 loci establish marsupial sequences as a model for phylogenetic footprinting.
Michael Addison Chapman
,
Fadi Charchar
,
+7 authors
Berthold Göttgens
Genomics
2003
Comparative genomic sequence analysis is a powerful technique for identifying regulatory regions in genomic DNA. However, its…Â
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Review
1993
Review
1993
TAL1, TAL2 and LYL1: a family of basic helix-loop-helix proteins implicated in T cell acute leukaemia.
Roman Bär
Seminars in cancer biology
1993
TAL1 gene rearrangement is the most common genetic defect associated with T cell acute lymphoblastic leukaemia (T-ALL). Tumour…Â
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1991
1991
Structure, chromosome mapping, and expression of the mouse Lyl-1 gene.
S S Kuo
,
Julia D. Mellentin
,
Neal G. Copeland
,
D. J. Gilbert
,
N. A. Jenkins
,
Michele Cleary
Oncogene
1991
The mouse Lyl-1 gene was cloned and shown to consist of four exons with extensive nucleotide and structural homology to the human…Â
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