LTK gene

Known as: leukocyte receptor tyrosine kinase, LEUKOCYTE TYROSINE KINASE, PROTEIN TYROSINE KINASE-1 
This gene plays a role in leukocyte tyrosine kinase signal transduction and diverse cellular regulatory pathways.
National Institutes of Health

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6 relations
LTK protein, humanLTK wt AlleleLigand BindingPhosphorylation
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Papers overview

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2018
2018
Gene expression microarray analysis reveals prognostic markers of survival in high grade astrocytomas.
OBJECTIVE High grade astrocytoma (HGA) as an aggressive brain tumor, is always correlated with poor prognosis. In this paper, we… (More)
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2012
2012
A simple, highly visual in vivo screen for anaplastic lymphoma kinase inhibitors.
Anaplastic lymphoma kinase (ALK) is an important drug target in many cancers, including lymphoma, neuroblastoma, and lung cancer… (More)
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Highly Cited
2008
Highly Cited
2008
Leukocyte Tyrosine Kinase Functions in Pigment Cell Development
A fundamental problem in developmental biology concerns how multipotent precursors choose specific fates. Neural crest cells… (More)
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2003
2003
Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus.
Systemic lupus erythematosus (SLE), a complex multigenic disease, is a typical antibody-mediated autoimmune disease characterized… (More)
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1999
1999
Diode laser thermokeratoplasty – first clinical experience
Purpose: Pulsed holmium lasers are currently used to correct hyperopia by means of laser thermokeratoplasty (LTK). Series of μs… (More)
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Highly Cited
1997
Highly Cited
1997
ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)
Anaplastic Lymphoma Kinase (ALK) was originally identified as a member of the insulin receptor subfamily of receptor tyrosine… (More)
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1997
1997
Darstellung von LTK-Läsionen durch optische Kurzkohärenztomographie (OCT) und Polarisationsmikroskopie nach Sirius-Rot-Färbung
Hintergrund: Für die Kontrolle der Laserdosis und der postoperativen Entwicklung bei Laserthermokeratoplastik (LTK) sind… (More)
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Highly Cited
1994
Highly Cited
1994
Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3.
Ki-1 lymphoma is a subtype of human malignant lymphoma characterized by the expression of CD30 (Ki-1) and a peculiar morphology… (More)
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1988
1988
Leukocytes express a novel gene encoding a putative transmembrane protein-kinase devoid of an extracellular domain
Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and… (More)
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1975
1975
Presence of a herpes simplex virus type 1 genome fragment in HSV-transformed cells.
LTK-cells infected with UV-irradiated HSV produce transformants that contain a thymidine kinase (TK) activity not found in the… (More)
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