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LTA4H gene

Known as: LEUKOTRIENE A4 HYDROLASE, LTA4H, Leukotriene A4 Hydrolase Gene 
This gene plays a role in leukotriene metabolism.
National Institutes of Health

Related topics

Related topics

5 relations
Eicosanoid ModulationHydrolysisLeukotriene A-4 Hydrolase, humanPeptide Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis
Significance Leukotriene B4 (LTB4) is a one of the most potent chemotactic agents known to date and participates in leukocyte… 
2016
2016
Thermodynamic properties of leukotriene A4 hydrolase inhibitors.
2015
2015
PENG: A Neural Gas-Based Approach for Pharmacophore Elucidation. Method Design, Validation, and Virtual Screening for Novel Ligands of LTA4H
The pharmacophore concept is commonly employed in virtual screening for hit identification. A pharmacophore is generally defined… 
2014
2014
Leukotriene haplotype × diet interaction on carotid artery hypertrophy and atherosclerosis in American Indians: the Strong Heart Family Study.
2012
2012
Genetic variation in members of the leukotrienes biosynthesis pathway confers risk of ischemic stroke in Eastern Han Chinese.
2011
2011
Well-Differentiated Liposarcoma of the Oesophagus: Clinicopathological, Immunohistochemical and Array CGH Analysis
Liposarcoma develops extremely rarely in the oesophagus. Microscopically, it exhibits subtle atypia of H&E-stained features… 
2010
2010
Modulating the Substrate Specificity of LTA4H Aminopeptidase by Using Chemical Compounds and Small‐Molecule‐Guided Mutagenesis
Leukotriene A4 hydrolase (LTA4H) is a bifunctional zinc‐containing enzyme with an epoxide hydrolase activity and an… 
Review
2009
Review
2009
Pharmacogenetics of asthma
Purpose of review Patient response to the asthma drug classes, bronchodilators, inhaled corticosteroids and leukotriene modifiers… 
2006
2006
A conserved tyrosine residue of Saccharomyces cerevisiae leukotriene A4 hydrolase stabilizes the transition state of the peptidase activity
Review
2002
Review
2002
Pharmacogenetics of asthma.
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