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LTA4H gene

Known as: LEUKOTRIENE A4 HYDROLASE, LTA4H, Leukotriene A4 Hydrolase Gene 
This gene plays a role in leukotriene metabolism.
National Institutes of Health

Papers overview

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2017
2017
Background Damaging inflammation is thought to contribute to the high morbidity and mortality of tuberculous meningitis (TBM… Expand
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2014
2014
RATIONALE Chronic neutrophilic inflammation is a hallmark in the pathogenesis of chronic obstructive pulmonary disease (COPD) and… Expand
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Highly Cited
2013
Highly Cited
2013
Maresins are produced by macrophages from docosahexaenoic acid (DHA) and exert potent proresolving and tissue homeostatic actions… Expand
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Review
2013
Review
2013
Tuberculous meningitis is especially common in young children and people with untreated HIV infection, and it kills or disables… Expand
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Highly Cited
2012
Highly Cited
2012
Susceptibility to tuberculosis is historically ascribed to an inadequate immune response that fails to control infecting… Expand
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Highly Cited
2010
Highly Cited
2010
Exposure to Mycobacterium tuberculosis produces varied early outcomes, ranging from resistance to infection to progressive… Expand
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2006
2006
Previous studies have shown that aberrant arachidonic acid (AA) metabolism, especially cyclooxygenase-2 (Cox-2) and 5… Expand
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Highly Cited
2006
Highly Cited
2006
Leukotrienes (LT) are a group of proinflammatory lipid mediators that are implicated in the pathogenesis and progression of… Expand
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Highly Cited
2006
Highly Cited
2006
RATIONALE Interpatient variability in montelukast response may be related to variation in leukotriene pathway candidate genes… Expand
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Highly Cited
2001
Highly Cited
2001
Leukotriene (LT) A4 hydrolase/aminopeptidase (LTA4H) is a bifunctional zinc enzyme that catalyzes the biosynthesis of LTB4, a… Expand
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