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LRP1B gene

Known as: Low Density Lipoprotein Receptor-Related Protein 1B Gene, LRP-deleted in tumors, LRPDIT 
This gene plays a role in low density lipoprotein metabolism.
National Institutes of Health

Related topics

Related topics

4 relations
Ligand BindingLow-Density Lipoprotein Receptor-Related Protein 1BReceptor Mediated EndocytosisReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Hypoxia induced microRNA-301b-3p overexpression promotes proliferation, migration and invasion of prostate cancer cells by targeting LRP1B.
2015
2015
Genome-wide haplotype association study identify TNFRSF1A, CASP7, LRP1B, CDH1 and TG genes associated with Alzheimer's disease in Caribbean Hispanic individuals
Alzheimer's disease (AD) is an acquired disorder of cognitive and behavioral impairment. It is considered to be caused by variety… 
2015
2015
LRP1B deletion is associated with poor outcome for glioblastoma patients
Review
2014
Review
2014
Trafficking regulation of proteins in Alzheimer’s disease
The β-amyloid (Aβ) peptide has been postulated to be a key determinant in the pathogenesis of Alzheimer’s disease (AD). Aβ is… 
2010
2010
Ectodomains of the LDL Receptor-Related Proteins LRP1b and LRP4 Have Anchorage Independent Functions In Vivo
Background The low-density lipoprotein (LDL) receptor gene family is a highly conserved group of membrane receptors with diverse… 
Highly Cited
2007
Highly Cited
2007
Ultradeep bisulfite sequencing analysis of DNA methylation patterns in multiple gene promoters by 454 sequencing.
We developed a novel approach for conducting multisample, multigene, ultradeep bisulfite sequencing analysis of DNA methylation… 
Review
2006
Review
2006
Modulation of β-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family
Amyloid-β peptide (Aβ) accumulation in the brain is an early, toxic event in the pathogenesis of Alzheimer's disease (AD). Aβ is… 
Highly Cited
2004
Highly Cited
2004
Frequent Silencing of Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B) Expression by Genetic and Epigenetic Mechanisms in Esophageal Squamous Cell Carcinoma
Low-density lipoprotein receptor-related protein 1B (LRP1B) is frequently deleted in tumors of various types, but its status and… 
Highly Cited
2004
Highly Cited
2004
Normal Development and Fertility of Knockout Mice Lacking the Tumor Suppressor Gene LRP1b Suggest Functional Compensation by LRP1
ABSTRACT LRP1b and the closely related LRP1 are large members of the low-density lipoprotein receptor family. At the protein… 
2004
2004
LRP1B Attenuates the Migration of Smooth Muscle Cells by Reducing Membrane Localization of Urokinase and PDGF Receptors
Objective—Studies on the involvement of low-density lipoprotein receptor relatives (LRs) in atherosclerosis have recently gained… 
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