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LPAR1 gene

Known as: LYSOPHOSPHATIDIC ACID RECEPTOR EDG2, vzg-1, EDG2 
National Institutes of Health

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Related topics

1 relation
S1PR1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Effective relief of neuropathic pain by adeno-associated virus-mediated expression of a small hairpin RNA against GTP cyclohydrolase 1
BackgroundRecent studies show that transcriptional activation of GTP cyclohydrolase I (GCH1) in dorsal root ganglia (DRG) is… 
Highly Cited
2007
Highly Cited
2007
LPA1 receptor activation promotes renal interstitial fibrosis.
Tubulointerstitial fibrosis in chronic renal disease is strongly associated with progressive loss of renal function. We studied… 
Highly Cited
2004
Highly Cited
2004
Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling
Lysophosphatidic acid (LPA) is a bioactive lipid with activity in the nervous system mediated by G-protein-coupled receptors… 
Highly Cited
2003
Highly Cited
2003
Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors.
Lysophosphatidic acid (LPA) exerts a variety of biological responses through specific receptors: three subtypes of the EDG-family… 
Highly Cited
2003
Highly Cited
2003
Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding
Lysophosphatidic acid (LPA) is a phospholipid that has extracellular signaling properties mediated by G protein–coupled receptors… 
Highly Cited
2003
Highly Cited
2003
Subtype-Selective Antagonists of Lysophosphatidic Acid Receptors Inhibit Platelet Activation Triggered by the Lipid Core of Atherosclerotic Plaques
Background—Lysophosphatidic acid (LPA) is a platelet-activating component of mildly oxidized LDL (mox-LDL) and lipids isolated… 
Review
2001
Review
2001
Lysophospholipid receptors.
Highly Cited
2000
Highly Cited
2000
Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species
Highly Cited
2000
Highly Cited
2000
Isolation and genetic mapping of a non-lethal rice (Oryza sativa L.) low phytic acid 1 mutation
Phytic acid (myo-inositol 1,2,3,4,5,6 hexakisphosphate) is the most abundant form of phosphorus (P) in seeds and is virtually… 
Highly Cited
1999
Highly Cited
1999
EDG3 is a functional receptor specific for sphingosine 1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16.
AGR16/H218/EDG5 and EDG1 are functional receptors for lysosphingolipids, whereas EDG2 and EGD4 are receptors for lysophosphatidic… 
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