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LNP 509

Known as: dicyclopropylmethyl-(4,5-dimethyl-4,5-dihydro-3H-pyrrol-2-yl)amine, lnp-509 
 
National Institutes of Health

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2 relations

Broader (2)

CyclopropanesPyrroles

Papers overview

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2006
2006
Opposite to α2-adrenergic agonists, an imidazoline I1 selective compound does not influence reflex bradycardia in rabbits
This work aimed to study the respective effects of central alpha2-adrenergic receptors (alpha2-ARS) and I1 imidazoline receptors… Expand
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2004
2004
Effects of centrally acting antihypertensive drugs on the microcirculation of spontaneously hypertensive rats.
We investigated the acute effects of centrally acting antihypertensive drugs on the microcirculation of pentobarbital… Expand
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2002
2002
Evidence for synergy between alpha(2)-adrenergic and nonadrenergic mechanisms in central blood pressure regulation.
BACKGROUND Both alpha(2)-adrenergic and non--alpha(2)-adrenergic mechanisms seem to be involved in the hypotensive effect of… Expand
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2001
2001
Synthesis and biological evaluation of pyrrolinic isosteres of rilmenidine. Discovery of cis-/trans-dicyclopropylmethyl-(4,5-dimethyl-4,5-dihydro-3H-pyrrol-2-yl)-amine (LNP 509), an I1 imidazoline…
To find new compounds selective for purported I1 imidazoline receptors (I1Rs) over I2 imidazoline binding sites (I2BS) and alpha2… Expand
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