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LMO2 gene

Known as: LMO2, RBTN2, RHOMBOTIN 2 
This gene plays a crucial role in hematopoietic development and is involved in transcriptional activation.
National Institutes of Health

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Related topics

10 relations
Acute lymphocytic leukemiaAngiogenic ProcessHematopoiesisHomo sapiens

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LMO2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Single Domain Intracellular Antibodies from Diverse Libraries
Interfering intracellular antibodies are valuable for biological studies as drug surrogates and as potential macromolecular drugs… 
2009
2009
Molecular outcome prediction in diffuse large-B-cell lymphoma.
To the Editor: Lenz et al. (Nov. 27 issue)1 report the results of an important study of gene expression and survival in patients… 
2008
2008
An antibody inhibitor of the LMO2-protein complex blocks its normal and tumorigenic functions
The LIM-domain protein LMO2 is a T-cell oncogenic protein first recognized by gene activation through chromosomal translocations… 
2005
2005
Negative regulatory elements are present in the human LMO2 oncogene and may contribute to its expression in leukemia.
Review
2002
Review
2002
Developmental expression of serum response factor in the rat central nervous system.
Highly Cited
2001
Highly Cited
2001
Analysis of the V(D)J Recombination Efficiency at Lymphoid Chromosomal Translocation Breakpoints*
Chromosomal translocations and deletions are among the major events that initiate neoplasia. For lymphoid chromosomal… 
Highly Cited
1999
Highly Cited
1999
The effect of chromosomal translocations in acute leukemias: the LMO2 paradigm in transcription and development.
Two general features have emerged about genes that are activated after chromosomal translocations in acute forms of cancer. The… 
Highly Cited
1997
Highly Cited
1997
Expression of LIM Protein Genes Lmo1, Lmo2, andLmo3 in Adult Mouse Hippocampus and Other Forebrain Regions: Differential Regulation by Seizure Activity
The LIM domain is a zinc-binding amino acid motif that characterizes various proteins which function in protein–protein… 
1997
1997
T-cell oncogene rhombotin-2 interacts with retinoblastoma-binding protein 2
The LIM domain protein rhombotin-2 (RBTN-2/TTG-2/Lmo2) has distinct functions in erythropoiesis and in T-cell leukemogenesis… 
1995
1995
Functional diversity of LIM proteins: amino-terminal activation domains in the oncogenic proteins RBTN1 and RBTN2.
The RBTN1 and RBTN2 genes are activated by distinct translocations involving chromosome 11 in some T cell acute leukaemias. The… 
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