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LIN28A wt Allele

Known as: CSDD1, Lin-28 Homolog A (C. Elegans) wt Allele, LIN-28 
Human LIN28 wild-type allele is located in the vicinity of 1p36.11 and is approximately 19 kb in length. This allele, which encodes lin-28 homolog A… 
National Institutes of Health

Related topics

Related topics

3 relations
1p36.11Genetic Translation Process

Broader (1)

LIN28A gene

Papers overview

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Highly Cited
2015
Highly Cited
2015
Lin28 promotes the proliferative capacity of neural progenitor cells in brain development
Neural progenitor cells (NPCs) have distinct proliferation capacities at different stages of brain development. Lin28 is an RNA… 
Highly Cited
2013
Highly Cited
2013
Fetal Deficiency of Lin28 Programs Life‐Long Aberrations in Growth and Glucose Metabolism
LIN28A/B are RNA binding proteins implicated by genetic association studies in human growth and glucose metabolism. Mice with… 
Review
2013
Review
2013
Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier
The differentiation and reprogramming of cells are accompanied by drastic changes in the epigenetic profiles of cells. Waddington… 
Highly Cited
2010
Highly Cited
2010
Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells.
A relatively rare aldehyde dehydrogenase 1 (ALDH1)-positive "stem cell-like" subpopulation of tumor cells has the unique ability… 
Highly Cited
2009
Highly Cited
2009
A role for Lin28 in primordial germ cell development and germ cell malignancy
The rarity and inaccessibility of the earliest primordial germ cells (PGCs) in the mouse embryo thwart efforts to investigate… 
Highly Cited
2009
Highly Cited
2009
Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let‐7
Raf kinase inhibitory protein (RKIP) negatively regulates the MAP kinase (MAPK), G protein‐coupled receptor kinase‐2, and NF‐κB… 
Highly Cited
2009
Highly Cited
2009
The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse
BackgroundLife-long production of spermatozoa depends on spermatogonial stem cells. Spermatogonial stem cells exist among the… 
Highly Cited
2009
Highly Cited
2009
Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II.
Highly Cited
2002
Highly Cited
2002
Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation.
The heterochronic gene lin-28 of the nematode Caenorhabditis elegans controls the relative timing of diverse developmental events… 
Highly Cited
1989
Highly Cited
1989
A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans
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