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LIMK1 wt Allele

Known as: LIM Domain Kinase 1 wt Allele, LIMK 
Human LIMK1 wild-type allele is located in the vicinity of 7q11.23 and is approximately 39 kb in length. This allele, which encodes LIM domain kinase… 
National Institutes of Health

Related topics

Related topics

9 relations
7q11.23CCR3 Signaling PathwayCytoskeletal ModelingHomo sapiens

Broader (1)

LIMK1 gene

Papers overview

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2018
2018
VEGF Triggers the Activation of Cofilin and the Arp2/3 Complex within the Growth Cone
A crucial neuronal structure for the development and regeneration of neuronal networks is the axonal growth cone. Affected by… 
2015
2015
LIM Kinase, a Newly Identified Regulator of Presynaptic Remodeling by Rod Photoreceptors After Injury.
PURPOSE Rod photoreceptors retract their axon terminals and develop neuritic sprouts in response to retinal detachment and… 
2012
2012
Cell Cycle and Senescence Knockdown of PAK 4 or PAK 1 Inhibits the Proliferation of Mutant KRAS Colon Cancer Cells Independently of RAF / MEK / ERK and PI 3 K / AKT Signaling
The p21-activated kinase (PAK) serine/threonine kinases are important effectors of the small GTPases Rac and Cdc42, and play… 
2011
2011
Overexpression of LIMK1 promotes migration ability of multidrug-resistant osteosarcoma cells.
Multidrug resistance (MDR) to chemotherapy is a major obstacle in the treatment of cancer and the resistance process is… 
Highly Cited
2008
Highly Cited
2008
A δ-Catenin Signaling Pathway Leading to Dendritic Protrusions*
δ-Catenin is a synaptic adherens junction protein pivotally positioned to serve as a signaling sensor and integrator. Expression… 
2008
2008
Reduction of Akt2 expression inhibits chemotaxis signal transduction in human breast cancer cells.
Review
2007
Review
2007
A discourse on cancer cell chemotaxis: Where to from here?
The study of cancer cell chemotaxis on two‐dimensional surfaces in vitro has relevance to the diverse migratory behaviours… 
2007
2007
Distinct Effects of Contraction Agonists on the Phosphorylation State of Cofilin in Pulmonary Artery Smooth Muscle
We hypothesized that agonist-induced contraction correlates with the phospho-cofilin/cofilin (P-CF/CF) ratio in pulmonary artery… 
2004
2004
LIM kinase 1: evidence for a role in the regulation of intracellular vesicle trafficking of lysosomes and endosomes in human breast cancer cells.
LIM kinase (LIMK) plays a critical role in stimulus-induced remodeling of the actin cytoskeleton by linking signals from the Rho… 
1999
1999
Cloning and characterization of the alternative promoter regions of the human LIMK2 gene responsible for alternative transcripts with tissue-specific expression.
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