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LGK974

Known as: PORCN inhibitor LGK974 
National Institutes of Health

Papers overview

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2020
2020
Targeted therapy for kidney cancer has achieved significant clinical results. However, because most patients who use targeted… 
Highly Cited
2018
Highly Cited
2018
Glioblastoma is the most aggressive type of glioma. The Wingless (Wnt) signaling pathway has been shown to promote stem cell… 
2018
2018
WNT signaling is involved in the tumorigenesis of various cancers and regulates bone homeostasis. Palmitoleoylation of WNTs by… 
2018
2018
Background: Dysregulated Wnt/β-catenin signaling has been linked to several cancers, including pancreatic cancer (PC) and… 
2017
2017
Introduction Endocrine therapy of breast cancer, which either deprives cancer tissue of estrogen or prevents estrogen pathway… 
2016
2016
Objective: Glioma Stem Cells (GSCs) are considered to be responsible for Glioblastoma9s (GBM’s) dismal prognosis. WNT signaling… 
2015
2015
Nuclear receptor binding protein 1 (NRBP1) is a highly conserved protein that is ubiquitously expressed across cell types in… 
2014
2014
BCR-ABL tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myeloid leukemia (CML). However, TKIs are…