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LGALS8 wt Allele

Known as: Gal-8, PCTA-1, Lectin, Galactoside-Binding, Soluble, 8 (Galectin 8) wt Allele 
Human LGALS8 wild-type allele is located within 1q42-q43 and is approximately 31 kb in length. This allele, which encodes galectin-8 protein, plays a… 
National Institutes of Health

Related topics

Related topics

10 relations
1q42-q43ApoptosisCell AdhesionCell Cycle Control

Broader (1)

LGALS8 gene

Papers overview

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Highly Cited
2014
Highly Cited
2014
Control of Angiogenesis by Galectins Involves the Release of Platelet-Derived Proangiogenic Factors
Platelets contribute to vessel formation through the release of angiogenesis-modulating factors stored in their α-granules… 
Review
2014
Review
2014
Galectin-8: a matricellular lectin with key roles in angiogenesis.
Galectin-8 (gal-8) is a "tandem-repeat"-type galectin, containing two carbohydrate recognition domains connected by a linker… 
Highly Cited
2011
Highly Cited
2011
Modulation of endothelial cell migration and angiogenesis: a novel function for the “tandem‐repeat” lectin galectin‐8
Angiogenesis, the growth of new capillaries from preexisting blood vessels, is a complex process involving endothelial cell (EC… 
Highly Cited
2009
Highly Cited
2009
Galectin‐8 provides costimulatory and proliferative signals to T lymphocytes
Galectin (Gal) constitute a family of carbohydrate‐recognizing molecules ubiquitously expressed in mammals. In the immune system… 
Highly Cited
2009
Highly Cited
2009
Galectin-8 Induces Apoptosis in Jurkat T Cells by Phosphatidic Acid-mediated ERK1/2 Activation Supported by Protein Kinase A Down-regulation*
Galectins have been implicated in T cell homeostasis playing complementary pro-apoptotic roles. Here we show that galectin-8 (Gal… 
Highly Cited
2007
Highly Cited
2007
Beneficial effect of galectin 9 on rheumatoid arthritis by induction of apoptosis of synovial fibroblasts.
OBJECTIVE To compare the expression of galectin 9 (Gal-9) in synovial tissue (ST) from rheumatoid arthritis (RA) patients and… 
Highly Cited
2007
Highly Cited
2007
The Involvement of CD44 and Its Novel Ligand Galectin-8 in Apoptotic Regulation of Autoimmune Inflammation1
The synovial fluid (SF) cells of rheumatoid arthritis (RA) patients express a specific CD44 variant designated CD44vRA. Using a… 
Highly Cited
2006
Highly Cited
2006
Galectin-8 binds specific beta1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells.
1999
1999
Expression of Po66-CBP, a type-8 galectin, in different healthy, tumoral and peritumoral tissues.
UNLABELLED A monoclonal antibody, Po66, recognized an antigen named Po66 carbohydrate binding protein (PO66-CBP), which was… 
1998
1998
The abundance of additional N-acetyllactosamine units in N-linked tetraantennary oligosaccharides of human Tamm-Horsfall glycoprotein is a donor-specific feature.
Previously, treatment of Tamm-Horsfall glycoprotein (THp) from different donors with endo-beta-galactosidase has been shown to… 
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