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LCP2 wt Allele
Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) wt Allele
Human LCP2 wild-type allele is located within 5q33.1-qter and is approximately 50 kb in length. This allele, which encodes lymphocyte cytosolic…
National Institutes of Health
SH2 domain-containing leukocyte protein, 76-kDa
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SLP-76 is required for high-affinity IgE receptor- and IL-3 receptor-mediated activation of basophils.
Corpus ID: 20611360
Basophils have been reported to play a critical role in allergic inflammation by secreting IL-4 in response to IL-3 or high…
SLP-65 Signal Transduction Requires Src Homology 2 domain-mediated Membrane Anchoring and a Kinase-independent Adaptor Function of Syk*
Journal of Biological Chemistry
Corpus ID: 20275416
The family of SLPs (Src homology 2 domain-containing leukocyte adaptor proteins) are cytoplasmic signal effectors of lymphocyte…
Retinoic acid induces expression of SLP-76: expression with c-FMS enhances ERK activation and retinoic acid-induced differentiation/G0 arrest of HL-60 cells.
J. L. Smith
Thomas J. Lamkin
European journal of cell biology
Corpus ID: 40556014
Retinoic acid (RA) is known to cause MAPK signaling which propels G0 arrest and myeloid differentiation of HL-60 human…
Novel Isoform of Lymphoid Adaptor FYN-T-binding Protein (FYB-130) Interacts with SLP-76 and Up-regulates Interleukin 2 Production*
The Journal of Biological Chemistry
Corpus ID: 20743465
T-cell activation involves the participation of protein-tyrosine kinases p56 lck and ZAP-70/SYK as well as lymphoid proteins such…
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