L870810

Known as: L-870,810 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2015
02420042015

Papers overview

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2015
2015
The purpose was to propose two-stage single-compartment models for evaluating dissolution characteristics in distal ileum and… (More)
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2012
2012
Among a large number of HIV-1 integrase (IN) inhibitors, the 8-hydroxy-[1,6]naphthyridines (i.e., L-870,810) were one of the… (More)
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2009
2009
We evaluated the human immunodeficiency virus type 1 (HIV-1) integrase coding region of the pol gene for the presence of natural… (More)
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2009
2009
A three-dimensional model of a complex between HIV-1 integrase (IN), viral DNA, and metal ions that we recently built was used as… (More)
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2008
2008
Resistance passage studies were conducted with five INIs (integrase inhibitors) that have been tested in clinical trials to date… (More)
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2008
2008
To gain further insight into the understanding of the antiviral resistance patterns and mechanisms of the integrase strand… (More)
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2007
2007
Treatment of feline immunodeficiency virus (FIV) infection has been hampered by the absence of a specific combination… (More)
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2007
2007
Human immunodeficiency virus type 1 (HIV-1) integrase (IN) inserts the viral DNA genome into host chromosomes. Here, by native… (More)
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2005
2005
Because of its unique role in the viral replication process, HIV-1 integrase (IN) is an important antiretroviral drug target. The… (More)
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Highly Cited
2004
Highly Cited
2004
The increasing incidence of resistance to current HIV-1 therapy underscores the need to develop antiretroviral agents with new… (More)
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