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L3MBTL3 gene

Known as: KIAA1798, L3MBTL3, l(3)mbt-like 3 (Drosophila) 
National Institutes of Health

Papers overview

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2019
2019
Medulloblastoma is the most common malignant brain tumor of childhood. Therapeutic approaches to medulloblastoma have led to… 
2018
2018
SOX2 is a dose-dependent master stem cell protein that controls the self-renewal and pluripotency or multipotency of embryonic… 
2018
2018
Multiple sclerosis (MS) is the most common inflammatory and chronic disease of the central nervous system (CNS). A complex… 
Highly Cited
2016
Highly Cited
2016
Genome-wide study in Germans identifies four novel multiple sclerosis risk genes and confirms already known gene loci. We… 
2016
2016
L3MBTL3 recognizes mono- and dimethylated lysine residues on histone tails. The recently reported X-ray cocrystal structures of… 
2014
2014
The histone code regulates a number of processes including transcription, DNA replication, and DNA repair. L3MBTL3 is a putative… 
Highly Cited
2013
Highly Cited
2013
We describe the discovery of UNC1215, a potent and selective chemical probe for the methyl-lysine (Kme) reading function of… 
Highly Cited
2013
Highly Cited
2013
Lysine methylation is a key epigenetic mark, the dysregulation of which is linked to many diseases. Small-molecule antagonism of… 
Highly Cited
2013
Highly Cited
2013
Although genome-wide association studies (GWAS) have identified a significant number of single-nucleotide polymorphisms (SNPs… 
2013
2013
We recently reported the discovery of UNC1215, a potent and selective chemical probe for the L3MBTL3 methyllysine reader domain…